双源 CT 灌注成像对急性胰腺炎严重程度的诊断价值  

Diagnostic value of siemens dual energy CT in severity analysis of acute pancreatitis

作　　者：倪健坤 徐东风 戴鸿志 沈莉 沈一易 

机构地区：[1]苏州市吴江区第一人民医院CT&MR室,江苏苏州215200

出　　处：《实用放射学杂志》2016年第2期220-223,258,共5页Journal of Practical Radiology

基　　金：基金项目：苏州市2013年度科技发展计划（应用基础研究-医疗卫生项目）（SYSD2013046）.

摘　　要：目的：探讨双源 CT 灌注成像在分析急性胰腺炎（AP）严重程度中的诊断价值。方法应用西门子双源 CT 对60例患者行胰腺 CT 灌注成像,包括正常组,轻症急性胰腺炎（MAP）组及重症急性胰腺炎（SAP）组各20例。使用西门子 MMWP 工作站后处理软件分别测量血流量（BF）、血容量（BV）、毛细血管表面通透性（PS）及平均通过时间（MTT）。分析 CT 灌注值在 AP 诊断和分析严重程度中的作用。结果 MAP 组、SAP 组的胰腺灌注参数 BF、BV 值较正常组显著降低（P 〈0.01）,MAP 组的 BF、BV 值显著高于 SAP 组（P 〈0.01）。MAP 组、SAP 组的 PS 值显著高于正常组（P 〈0.01）,MTT 各组间差异无统计学意义,但≥45岁组MAP 及 SAP 组 MTT 值明显高于正常组（P 〈0.05）。结论（1）CT 灌注参数 BF、BV 值在分析有无 AP 及 AP 严重程度中有诊断价值。（2）CT 灌注参数 PS 值可以作为判断是否存在 AP 的指标。（3）CT 灌注参数 MTT 值在大龄组（≥45岁）对诊断 AP 具有辅助参考意义。Objective To explore the diagnosis value of dual energy CT in severity analysis of acute pancreatitis.Methods Pancreas CT perfusion images of 60 patients were formatted using the method of Siemens dual energy CT.According to the severity of the acute pancreatitis,60 patients were divided into 3 groups：normal control （NC）group,mild acute pancreatitis （MAP）group and severe acute pancreatitis （SAP）group.Every group had 20 patients.Blood flow（BF）,blood volume（BV）,permeability of capillary surface （PS）and mean transit time（MTT）were calculated by Siemens MMWP workstation post process software.The meaning of these CT perfusion parameters for severity of acute pancreatitis was analyzed.Results Compared to the NC group,BF and BV in MAP,SAP group were reduced significantly （P 〈0.01）.BF and BV in MAP group were higher than those in SAP group （P 〈0.01）.PS in MAP,SAP group were higher than that in NC.MTT had no difference in three groups（P 〉0.05）.We also found in ≥45 years old patients,MTT in both MAP and SAP groups were higher than NC group（P 〈0.05）.Conclusion （1）BF and BV are useful in diagnosis of acute pancreatitis and analysis of severity of it.（2）PS is useful in diagnosis of acute pancreatitis.（3）MTT is useful in diagnosis of acute pancreatitis in elderly patients （≥45 years old）.

关 键 词：胰腺炎 计算机体层成像 

分 类 号：R576[医药卫生—消化系统] R814.42[医药卫生—内科学]