免疫缺陷大、小鼠在肿瘤学研究中的应用及实验中常见问题分析  

Application of immunodeficiency rats and mice and analysis of common problems in oncology research

作　　者：田枫[1] 张阔[1] 郑振辉[1] 

机构地区：[1]北京大学医学部实验动物科学部,北京100191

出　　处：《中国免疫学杂志》2016年第2期214-217,共4页Chinese Journal of Immunology

基　　金：北京高等学校青年英才计划项目(YETP0057)资助

摘　　要：目的:免疫缺陷大、小鼠在肿瘤学研究中发挥着越来越重要的地位,但由于其品系较多,实验者往往无从选择,本文对常用的免疫缺陷大、小鼠的特点及其应用进行分析探讨。方法:从免疫缺陷动物的分类、先天性免疫缺陷大、小鼠的特点及应用比较和肿瘤学研究中常见问题分析三个层次加以论述。结果:肿瘤学研究中应切实综合考虑各个免疫缺陷大、小鼠的特点。结论:为科研工作者使用免疫缺陷大、小鼠进行肿瘤学研究提供了有价值的参考资料。Objective：The immunodeficiency animals play more and more important role in oncology research. But researchers usually do not how to choose kinds of immunodeficiency rats and mice during experiments. In this paper, applications and characteristics of immunodeficiency animals were compared as well as some of the common problems were discussed in oncology study. Methods： Classification of the immunodeficiency animals, the characteristics and application of congenital immunodeficiency rats and mice, and common problem analysis in the study of oncology were explored. Results： The feature of various immunodeficiency rats and mice should be considered in the oncology experiments. Conclusion： The paper provide valuable reference for scientific researcher.

关 键 词：免疫缺陷 小鼠 大鼠 肿瘤学 

分 类 号：R73-35[医药卫生—肿瘤] Q95-331[医药卫生—临床医学]