长效利培酮微球、利培酮片、喹硫平片治疗精神分裂症的临床疗效  

The Clinical Efficacy of Long-acting Injectable Risperidone,Quetiapine Tablets,Risperidone Tablets in the Treatment of Schizophrenia

作　　者：刘丽娟 

机构地区：[1]辽宁省复员军人康宁医院,辽宁葫芦岛125100

出　　处：《中国医药指南》2016年第6期17-18,共2页Guide of China Medicine

摘　　要：目的观察长效利培酮微球(RLAI)、利培酮片及喹硫平片治疗精神分裂症的临床疗效。方法选取我院收治的精神分裂症患者63例,按照数字随机法随机分成3组,RLAI组采取RLAI治疗,利培酮片组采取利培酮片治疗,喹硫平片组采取喹硫平片治疗,比较3组的临床疗效。结果 RLAI组总有效率90.48%,利培酮片组总有效率80.95%,喹硫平片组总有效率85.71%,RLAI组总有效率略高于利培酮片组和喹硫平片组,差异无统计学意义(P>0.05)。结论 RLAI治疗精神分裂症总有效率较利培酮片及喹硫平片更高,且用药安全,是治疗精神分裂症的一线治疗药物。Objective To observe the effect of long-acting risperidone microsphere（RLAI）,the clinical curative effect Risperidone tablets and quetiapine tablets in the treatment of schizophrenia.Method Select our hospital 63 cases of patients with schizophrenia,according to randomly divided into 3 groups randomly,group RLAI took RLAI treatment.Results In RLAI group,the total efficiency of 90.48%,Risperidone Tablets group total effectiveness 80.95%,quetiapine piece group,the total efficiency of 85.71%,the total effective rate of RLAI group was slightly higher than that of Risperidone tablets group and quetiapine tablet group,no significant difference（P〉0.05）.Conclusion RLAI treatment of schizophrenia the total efficiency is Risperidone tablets and quetiapine higher,and drug safety,is the first-line therapy for the treatment of schizophrenia.

关 键 词：长效利培酮微球 利培酮片 喹硫平片 精神分裂症 

分 类 号：R749.3[医药卫生—神经病学与精神病学]