颅骨修补术后癫痫的相关危险因素分析  

An analysis of risk factors related to post-cranioplasty seizures

作　　者：蒋冰洁[1] 王玉海[1] 杨理坤 何建青 胡旭 陈卫良 

机构地区：[1]安徽医科大学无锡临床医学院,江苏省214004 [2]解放军第一〇一医院神经外科,全军颅脑损伤救治中心

出　　处：《江苏医药》2016年第4期408-411,共4页Jiangsu Medical Journal

摘　　要：目的分析颅骨修补术后癫痫发生的相关危险因素。方法 137例接受钛网片颅骨修补手术患者中,术后发生癫痫者34例。回顾患者的临床及影像学资料,分析颅骨修补术后癫痫的相关危险因素。结果钛网片颅骨修补术后癫痫的发生率为24.8%。预防性使用抗癫痫药物为颅骨修补术后癫痫的保护性因素(P<0.01),术后钛网板下积液和/或积血、颞部为主颅骨缺损、双侧颅骨缺损及颅骨缺损面积过大为术后癫痫发生的危险因素(P<0.05)。结论颅骨修补术后癫痫的发病率较高,预防性使用抗癫痫药物、防止术后钛网板下积液和/或积血有助于降低颅骨缺损修补术后癫痫的发生。Objective To analyze the risk factors related to post-cranioplasty seizures.Methods A total of 137 patients received cranioplasty with titanium mesh,of whom 34 cases were with postcranioplasty seizures.The clinical data were reviewed and the risk factors related to post-cranioplasty seizures were analyzed.Results The incidence of post-cranioplasty seizures after titanium mesh reparement was 24.82%.Prophylactic use of antiepileptic drugs was a protective factor for postcranioplasty seizures（P〈0.01）.The effusion/hematoma under titanium mesh,mainly temporal skull defect,bilateral skull defect and skull defect area were the risk factors for post-cranioplasty seizures（P〈0.05）.Conclusion The incidence of post-cranioplasty seizures is relatively higher.Prophylactic use of antiepileptic drugs and avoidance of post-cranioplasty effusion/hematoma under titanium mesh are helpful in reducing the incidence of post-cranioplasty seizures.

关 键 词：颅骨修补术 癫痫 钛网片 

分 类 号：R742[医药卫生—神经病学与精神病学]