老年前列腺癌患者病理分期与睡眠质量的研究  

Research of the Relationship between Sleep Quality and Pathological Staging of Prostate Carcinoma in Elderly Patients

作　　者：李丹[1] 母华国[1] 桑玲[1] 汤显斌[1] 

机构地区：[1]湖北医药学院附属太和医院病理科,湖北十堰442000

出　　处：《医学综述》2016年第5期997-999,共3页Medical Recapitulate

摘　　要：目的 探讨老年前列腺癌患者病理分期与睡眠质量的关系。方法 选取2013年11月至2014年9月湖北医药学院附属太和医院收治的226例老年前列腺癌患者作为研究对象,睡眠质量的评价采用匹兹堡睡眠质量指数,病理分期采用Gleason评分系统,临床分期依据TNM系统。结果PSQI平均得分为（8.3±6.2）分;睡眠质量差的102例（44.9%）,不同年龄段（60-69岁88例,70-79岁82例,80岁及以上56例）患者PSQI得分、睡眠质量比较差异有统计学意义（P〈0.05）;老年前列腺癌患者中高分化组82例,中分化组74例,低分化组70例,不同Gleason分级患者主观睡眠质量、入睡时间、睡眠时间、睡眠障碍、催眠药物、日间功能障碍、PSQI总分得分比较差异有统计学意义（P〈0.05）;不同Gleason分级（高分化组82例,中分化组74例,低分化组70例）患者的临床分期差异有统计学意义（P〈0.05）;老年前列腺癌患者中临床分期Ⅰ期63例,Ⅱ期69例,Ⅲ期41例,Ⅳ期有53例,不同临床分期患者的PSQI得分、睡眠质量比较差异有统计学意义（P〈0.05）。结论 老年前列腺癌患者睡眠质量较差,抗肿瘤治疗的同时应积极采取干预措施,以提高患者的睡眠质量。Objective To study the relationship between tumor pathological staging and sleep quality. Methods Total of 226 elderly patients with prostate cancer treated in Taihe Hospital of Hubei University of Medicine from Nov. 2013 to Sep. 2014 were included as the research objects. We used the Pittsburgh sleep quality index（PSQI） to evaluate the quality of sleep in patients. Gleason scoring system was used to collect the patients＇ tumor staging. We used TNM system to identify the clinical stage of prostate cancer. Results The average PSQI score was （ 8.3 ± 6. 2 ） scores. The incidence of poor sleep quality was 102 cases （44. 9% ）. The sleep quality and PSQI score between the different age groups（88 cases of 60-69 years,82 cases of 70-79 years old ,56 cases of 〉 80 years old） had statistically significant differences（ P 〈 0.05 ）. The high differentiation group had 82 cases, middle differentiation group 70 cases and low differentiation group 74 cases. The subjective sleep quality, time to fall asleep, sleep time, sleep disorders, hypnotic drugs, daytime dysfunction,PSQI scores with different Gleason stages had statistically significant differences（P 〈0.05）. The tumor clinical stage in patients with different Gleason score had statistically significant differences （P 〈 0. 05）. There were 63 cases of tumor clinical stage I ,69 cases of stage 11,41 eases of stage III ,and 53 cases of stage IV. The sleep quality and PSQI score in patients with different tumor clinical stages had statistically significant differences （ P 〈 0. 05 ）. Conclusion The sleep quality of elderly patients with prostate cancer is poor,and active intervention should be given along with the anti-tumor therapy,so as to improve the sleep quality of the patients.

关 键 词：前列腺癌 老年 病理分期 睡眠质量 

分 类 号：R36[医药卫生—病理学]