C反应蛋白对恶性肿瘤的意义  

The significance of CRP in malignant tumor

作　　者：高瑞[1] 骆玉霜[1] 尹晓菊 赵君慧[1] 

机构地区：[1]青海大学附属医院肿瘤二病区,西宁810001

出　　处：《实用肿瘤学杂志》2016年第1期84-87,共4页Practical Oncology Journal

摘　　要：机体在受到外伤、感染时，由肝脏产生的血清C反应蛋白（C—reactiveprotein，CRP）浓度升高，并通过调节吞噬细胞清除病原菌及坏死组织，从而参与机体的体液免疫。恶性肿瘤的发生、发展常伴随复杂的炎症反应通路，血清CRP浓度会随着肿瘤的进展与转归而发生变化，CRP在恶性肿瘤的良恶性鉴别、早期诊断、病理分期、淋巴结转移、组织学特点、预后、治疗等方面均有一定的相关性，从而有望成为恶性肿瘤的临床筛查指标。When the body is attacked by trauma and infection, the serum C - reactive protein（CRP） con- centration which is produced by the liver will increase. CRP participates in the body＇s humoral immunity through regulating the phagocytic cells to clear the pathogenic bacteria and necrotic tissue. The occurrence and develop- ment of malignant tumor is associated with complex inflammatory response pathway. Serum CRP concentration will change with the progress and remission of tumor. CRP is associated with differentiation of benign and malignant, the early diagnosis, the pathological stage, the lymph node metastasis, the organizational characteristics, the prognosis, and the treatment of malignant tumor. It is expected to be a clinical screening indicator of malignant tumor.

关 键 词：C反应蛋白 恶性肿瘤 早期诊断 预后 

分 类 号：R730.3[医药卫生—肿瘤]