后肾腺瘤的组织病理学特点及文献分析  

Histopathologic Features and Literature Review of Metanephric Adenoma

作　　者：周红艳[1,2] 王成鑫[1,2] 陈琼霞[1,2] 刘丽江[1,2] 

机构地区：[1]江大病理诊断所,湖北武汉430056 [2]江汉大学医学院病理学与病理生理学教研室,湖北武汉430056

出　　处：《江汉大学学报（自然科学版）》2016年第1期64-67,共4页Journal of Jianghan University：Natural Science Edition

摘　　要：目的后肾腺瘤是泌尿系统罕见肿瘤,对其病理特征、鉴别诊断及预后进行分析。方法收集2例手术切除的后肾腺瘤标本,应用常规病理学检查、免疫组织化学检查方法,并结合文献进行分析归纳其病理特点。结果 2例后肾腺瘤均为境界清楚的肿块;镜下瘤细胞小而密集,排列成呈腺泡状、腺管状及实性小巢状结构;核圆形、椭圆形,胞浆稀少、淡染;可见乳头样及不成熟肾小球样结构。免疫组织化学染色WT1、CD57、Vimentin阳性,CK7、AMACR阴性。结论后肾腺瘤为罕见的肾脏原发性上皮源性良性肿瘤,依据形态学特点及免疫组织化学染色结果可正确诊断。Objective Metanephric adenoma （MA） is a rare tumor of the urinary system. Its histopatholgy features, differential diagnosis and prognosis were analyzed. Methods Two cases of MA recently diagnosed in our institute were observed and analyzed in the gross, histopathological features and immunohistochemical features. Pathological features were concluded based on clinical information extracted from the medical records and literature review. Results Both tumors were masses with a clear boundary. They also had distinct feature in histology as small cells with high ratio of nucleus to cytoplasm, no nuclear atypia or mitotic figures. The tumor exhibited well-organized tubules, small cell nests, glomeruloid bodies, and sharply demarcated from the adjacent renal parenchyma. The expression of Vimentin , WT1 and CD57 were positive while CK7, AMACR were negative. Conclusion Metanephric adenoma is a rare kidney primary epithelial origin benign tumor, based on morphological characteristics and immunohistochemical staining results, it can be correctly diagnosed.

关 键 词：后肾腺瘤 病理学特征 免疫组织化学 

分 类 号：R737.110.2[医药卫生—肿瘤]