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作 者:王艳[1] 张艳卿[1] 童莉[1] 李莉[1] 刘丽娟[1]
机构地区:[1]衡水市哈励逊国际和平医院小儿内科,河北衡水053000
出 处:《中国医学装备》2016年第2期86-88,共3页China Medical Equipment
摘 要:目的:观察肝病治疗仪辅助治疗药物性肝损伤(DILI)的效果。方法:回顾性选取60例药物性肝损伤患者,按照随机数表法将其分为对照组与治疗组,每组30例。对照组给予常规保肝药物治疗;治疗组在上述治疗基础上联合应用肝病治疗仪治疗,疗程为4周。检测两组患者治疗前及治疗后血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、γ-转肽酶(γ-GT)及总胆红素(TB)水平,并评估治疗效果。结果:治疗组治疗总有效率为93.3%,对照组治疗总有效率为73.3%,治疗组较对照组明显提高(x^2=4.98,P<0.05)。疗程结束时治疗组患者血清ALT、AST、γ-GT及TB水平较对照组显著下降,两组比较差异均有统计学意义(t=5.88,t=4.78,t=6.23,t=4.66;P<0.05)。结论:肝病治疗仪能辅助治疗药物性肝损伤,并可提高治疗效果。Objective: To observe the therapeutic effect of HD-91- Ⅱ assistant therapy instrument for liver disease to treat patients with drug induced liver injury. Methods: Sixty cases with drug induced liver injury were selected into two groups (treatment group and control group) randomly. The control group was treated by routine drugs, and the treatment group was treated by both routinedrugs and HD-91-Ⅱ liver disease therapy instrument. All the cases were treated for 4 weeks. The serum levels of ALT, AST, γ-GT, TB level were detected before and after treatment to evaluate the curative effects. Results: The total effective rate of the treatment group was 95.5%, the effective rate of the control group was 75.5%, there was significantly different in two groups. And at the end of the treatment, the serum levels of ALT, AST, γ-GT, TB level of treatment group were also lower than control group. Conclusion: HD-91-Ⅱ liver disease therapy instrument can provide treatment to patients with drug induced liver injury, and can improve the therapeutic effect.
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