正常人模式脉冲与模式翻转多焦视诱发电位的比较  

Comparison of Pattern-pulse and Pattern-reversal Multifocal Visual Evoked Poten-tials in Normal Individuals

作　　者：朱镕霆 刘兴本[1] 徐晓明[1] 郑传斐[1] 

机构地区：[1]中国医科大学法医学院法医临床教研室,辽宁沈阳110001

出　　处：《法医学杂志》2016年第1期35-39,共5页Journal of Forensic Medicine

摘　　要：目的比较正常人模式脉冲多焦视诱发电位(pattern-pulse multifocal visual evoked potential,PPmf VEP)与模式翻转多焦视诱发电位(pattern-reversal multifocal visual evoked potential,PRmf VEP)的优缺点,观察多焦视诱发电位(mf VEP)的双眼对称性。方法采用Vision Monitor多焦视觉电生理仪检测系统行mf VEP检查,应用t检验和方差分析对两种VEP的主波(P1)、波幅、信噪比及双眼对称性进行统计分析。结果 PPmf VEP与PRmf VEP P1波幅和信噪比均在中央视野最大,并随离心度的增加呈减小趋势,下降速度由快渐趋平缓。在中央视网膜PPmf VEP波幅的变异系数明显小于PRmf VEP,而在周围视网膜则与之相反;PPmf VEP与PRmf VEP双眼对称象限的P1波幅及信噪比差异均无统计学意义(P>0.05),双眼同侧象限的波幅差异均大于对称象限。结论 mf VEP能准确、客观地反映视网膜不同部位的视功能;PPmf VEP较PRmf VEP能更好地反映中央视网膜的视功能状况,而在周边视网膜没有优势;在中央视网膜,PPmf VEP较PRmf VEP稳定;而在外周视网膜,PRmf VEP较PPmf VEP稳定;mf VEP在同一个体双眼之间存在对称性。Objective To compare pattern-pulse multifocal visual evoked potential （PPmfVEP） with pattern- reversal multifocal visual evoked potential （PRmfVEP）, and to investigate the symmetry of mfVEP be- tween both eyes in normal individuals. Methods The multifocal Vision Monitor was used to observe the mfVEP. T-test and ANOVA were used to analyze P1 wave, amplitude and signal noise ratios （SNR） of two mfVEPs. Results The SNR and the P1 amplitude reached the maximum at the central visual field and decreased with the increase of eccentricity, and then decreased slowly. The amplitude of the PPmfVEP was significantly smaller than the PRmfVEP in the central retina, while in the peripheral retina the re- sult was exactly the opposite. SNR and amplitude of the PRmfVEP showed no statistical difference in both eyes （P〉0.05）. The variance of the amplitude at the same side of visual field was larger than that at the symmetrical visual quadrant. Conclusion mfVEP can reflect the visual function in different parts of retina objectively and exactly. PPmfVEP reflect the vision function of the central retina better than PRmfVEP. The stability of PPmfVEP is better than PRmfVEP in the central retina, while the result is opposite in the peripheral retina. The mfVEP is symmetrical in both eyes of the same individual.

关 键 词：法医学 诱发电位 视觉 模式翻转多焦视诱发电位 模式脉冲多焦视诱发电位 

分 类 号：R770.43[医药卫生—眼科]