高危型人乳头瘤病毒感染女性及其配偶病毒检测结果分析  

Analysis of virus test results on 120 couples which wives infected with high-risk human papillomavirus

作　　者：刘学伟[1] 赵学英[1] 张喜庄[1] 杨永军[1] 杨继宏[1] 张慧[1] 

机构地区：[1]华北石油管理局总医院,河北任丘062552

出　　处：《现代中西医结合杂志》2016年第8期807-809,864,共4页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：河北省医学科研重点课题计划项目(20150823)

摘　　要：目的研究高危型人乳头瘤病毒(HPV)感染女性及其配偶病毒感染状况及HPV亚型分布,分析夫妻共患率。方法对120例经宫颈分泌物检测确诊高危型HPV阳性患者HPV亚型分布情况进行分析,并采集患者配偶尿道口上皮细胞和分泌物进行高危型HPV检测并分型,将检测结果与其妻子HPV检测结果进行对照分析。结果 120例女患者共检测到高危型HPV亚型8种,常见亚型为16,58,18,52和33型。120例女患者配偶共检测到高危型HPV感染52例(43.33%),常见亚型为16,18,58,52和33亚型。夫妻HPV吻合率为15.83%(19/120)。结论高危型HPV感染女性的配偶也是病毒感染的高危人群。女性一旦检测出高危型HPV感染阳性,有必要对其配偶进行HPV筛查,并将其纳入HPV感染的管理、治疗和跟踪检测范围。Objective It is to study the infection status of high risk human papillomavirus（ HR- HPV） and the distribution of HR- HPV subtypes in a man whose wife had been infected,and to analysis the concordance infection rate in couples.Methods Urethra epithelial cells and urethral secretions of 120 males whose wife infected with HR- HPV had been collected to detect 13 kinds of HPV subtypes. The result of HPV subtypes was been analysised with the results of his wife＇s. Results 8kinds of HR- HPV subtypes from 120 cases of women ＇s cervix swabs were detected. The common HR- HPV subtypes in women were： HPV16,58,18,52,33. 52 cases had been infected HR- HPV in male,the infection rate was 43. 33%. The common HR- HPV subtypes in men were： HPV16,18,58,52,33. The concordance infection rate in couples was 15. 83%（ 19 /120）. Conclusion Male whose wife infected with HR- HPV is at high risk of infection. It is necessary to carry out HPV screening for her husband once womon have detected a HR- HPV infection. Male whose wife infected with HR- HPV should be included in the range of management,treatment and follow-detection of the HPV infection.

关 键 词：男性 人乳头瘤病毒感染 基因检测 

分 类 号：R711.7[医药卫生—妇产科学]