血管母细胞瘤的MRI及MRS特点分析  

The MRI and MRS characteristics of hemangioblastoma

作　　者：郭丽萍[1] 李文菲[1] 牛晨[1] 马雪英[1] 梁丰丽 韩芳[2] 郭苏晋 张明[1] 

机构地区：[1]西安交通大学第一附属医院影像科,陕西西安710061 [2]大连医科大学附属大连市第三人民医院影像科,辽宁大连116033 [3]解放军323医院影像科,陕西西安710000

出　　处：《现代肿瘤医学》2016年第7期1125-1129,共5页Journal of Modern Oncology

基　　金：国家自然科学基金(编号:81171318)

摘　　要：目的:对血管母细胞瘤的MRI及MRS特点进行分析,提高对该病的认识并探讨MRI联合MRS检查对该病的诊断价值。方法:回顾性分析经病理证实的21例血管母细胞瘤的临床及影像学资料,分析病变部位、MRI及MRS特点及其与患者的预后关系。结果:21例病例中,囊实性病变19例,呈典型"大囊小结节"样改变,实质性者2例。MRI表现为病变囊性部分呈长T1长T2信号,增强扫描18例未见强化,1例囊壁轻微强化;附壁结节及病变实质部分T1WI呈等或稍低信号,T2WI呈等或稍高信号,增强扫描明显强化,实质性病变内可见血管流空、脂肪及脑膜强化信号。MRS示病变实性部分Cho及Cr峰明显增高,NAA峰明显减低,可见高耸的"LL"峰。3例VHL中2例伴有其他肿瘤。结论:血管母细胞瘤的MRI表现具有特征性,在掌握典型血管母细胞瘤MRI特点的基础上,MRS可以提供更多信息以提高对该病的早期诊断率。Objective： To increase awareness and explore the diagnostic value of MRI combinated with MRS examination for hemangioblastoma by analyzing its MRI and MRS characteristics. Methods： To analysis the features of hemangioblastoma about site,MRI and MRS features and their relationship with prognosis,a retrospective analysis of 21 cases of hemangioblastoma confirmed by pathology was made. Results： In 21 cases,there were 19 cases of cystic- solid lesions with typical sign of big cyst with mural nodules,solid lesions for 2 cases. The cystic part showed hypointensity on T1 WI and hyperintensity on T2 WI with invisiable enhancement in 18 cases and slight enhancement in 1 case.The mural nodules and solid part showed iso- / hypo- intensity on T1 WI and iso- / hyper- intensity on T2 WI with obvious enhancement and signs of blood flow void and fat within tumors and enhanced dura. MRS showed increased Cho and Cr peak and decreased NAA and ＂ LL＂ peak within solid part of tumors. Two of the three cases of VHL accompanied with other tumors. Conclusion： Hemangioblastoma is characterized by large cyst with mural nodules. In addition to mastering the typical MRI features,MRI combined with MRS examination can provide more infromation to improve its early diagnostic rate.

关 键 词：血管母细胞瘤 磁共振成像 磁共振波谱成像 

分 类 号：R732.2[医药卫生—肿瘤]