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机构地区:[1]河北工程大学附属医院肿瘤科,河北邯郸056002
出 处:《世界中医药》2015年第A02期1223-1226,共4页World Chinese Medicine
基 金:河北省科技支撑计划项目,项目编号:14277731D
摘 要:局部晚期和复发性宫颈癌死亡率极高,虽然近几年手术技巧、放疗设备及治疗技术的改进延长了病人的生存时间,提高了病人的生活质量,但临床对于局部晚期和复发性宫颈癌的治疗疗效依然不甚满意,治疗后最主要的失败原因是宫颈的局部复发,其次为远处转移,复发后的宫颈癌治疗十分棘手,预后很差,平均生存期仅为7个月,中位生存时间约5~18个月.针对对晚期和复发性宫颈癌的治疗现多采用多种手段的综合治疗,本文从手术、放疗、化疗、介入治疗、靶向治疗、基因技术和疫苗接种等几个方面进行阐述,并分析现存问题及今后的研究发展方向.Cervical cancer is the second malignant tumor in female, especially the local advanced and recurrent cervical cancer have high mortality. In recent years, although the surgical techniques and radiotherapy equipment in continuous improvement and the treatment technology has great progress, that prolong the survival time and improve the quality of life of patients, but the treatment result of locally advanced and recurrent cervical cancer still poor. Relapse is the most common reasons for failure after the treatment, it is very difficult for re-treatment and the prognosis is very poor. The average survival period for relapse patients was 7 months, the median survival time was only about 5-18 months. Therefore, the recurrent and refractory cervical cancer has become the focus of clinical treatment.Now, at home and abroad, for the advanced and recurrent cervical cancer, the treatment tend to use a variety of means of treatment. In this paper, we illustrate from surgery, radiotherapy and chemotherapy, interventional therapy, targeted therapy, gene technology and vaccination, and point out the existing problems and future research direction.
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