伴代谢综合征精神分裂症患者前瞻记忆研究  

Study on prospective memory in schizophrenia patients with concomitant metabolism syndrome

作　　者：吴庆[1] 王莹[2] 王莉[1] 黄英[1] 费龙才[1] 靳胜春[1] 刘兵[1] 张珉[1] 陈彬彬[1] 沈晓霜 

机构地区：[1]合肥市第四人民医院临床心理科,合肥230022 [2]合肥市第四人民医院老年心理科,合肥230022

出　　处：《中华行为医学与脑科学杂志》2016年第2期149-152,共4页Chinese Journal of Behavioral Medicine and Brain Science

摘　　要：目的研究伴代谢综合征精神分裂症患者的基于事件前瞻记忆（EBPM）和基于时间前瞻记忆（TBPM）的特点，为认知功能早期干预提供理论依据。方法对50例符合入组标准的伴代谢综合征精神分裂症患者以及年龄、性别、受教育程度相匹配的50名无代谢综合征精神分裂症患者实施前瞻记忆的神经心理学测试。结果伴代谢综合征精神分裂症患者组EBPM评分为（3．46±0．91）分，对照组EBPM评分为（3．86±0．81）分，两组之间差异有统计学意义（t=-2．326，P=0．022）。伴代谢综合征精神分裂症患者组TBPM评分为（3．02±1．12）分，对照组TBPM评分为（3．78±0．89）分，两组之间差异有统计学意义（t=-3．770，P=0．000）。结论伴代谢综合征精神分裂症患者相对无代谢综合征精神分裂症患者存在更严重的前瞻记忆功能损害。Objective To investigate the event-based prospective memory（EBPM）and time-based prospective memory（TBPM） in schizophrenia patients with concomitant metabolism syndrome,and to provide theory basis for early intervention and treatment.Methods According to inclusion standard, 50 schizophrenia patients with concomitant metabolism syndrome and 50 schizophrenia patients without metabolism syndrome matched in age,gender and education were assessed with a neuropsychologieal battery of tests including EBPM and TBPM tasks.Results In the EBPM task,there was significant difference between schizophrenia patients with and without metabolism syndrome （3.46±0.91 vs 3.86±0.81, t=-2.326, P= 0.022）.A statistically signifieant difference in TBPM was observed between schizophrenia patients with and without metabolism syn- drome （3.02±1.12vs3.78±0.89, t=-3.770, P= 0.000） .Conclusion The schizophrenia patients with metabolism syndrome have severer prospective memory impairment than those without metabolism syndrome.

关 键 词：代谢综合征 精神分裂症 前瞻记忆 

分 类 号：R749.3[医药卫生—神经病学与精神病学]