复合乳酸菌治疗不同程度食欲减退的慢性阻塞性肺疾病急性加重的价值  

Effects of lactobacillus complex capsules in patients with acute exacerbation of chronic obstructive pulmonary disease and different degrees anorexia

作　　者：李健[1] 陈锦平[1] 彭玲[1] 刘大鹰[1] 

机构地区：[1]柳州市柳铁中心医院呼吸内科,广西壮族自治区545007

出　　处：《实用医学杂志》2016年第3期392-395,共4页The Journal of Practical Medicine

基　　金：广西卫生厅自筹经费课题项目(编号:Z2011235);柳州市科学研究与技术开发计划课题资助(编号:2013J030413)

摘　　要：目的：研究复合乳酸菌治疗不同程度食欲减退的慢性阻塞性肺疾病急性加重期（AECOPD）的价值。方法：纳差评分1分和2～5分AECOPD患者各100例，分别给予常规[1分组（对照组1）和2～5分组（对照组2）各50例]和常规＋复合乳酸菌治疗[1分组（治疗组1）和2～5分组（治疗组2）各50例]。记录各组住院时间、炎症指标、血气、肺功能、临床症状、病死率等和复合乳酸菌不良反应。结果：治疗后治疗组2血白细胞计数（WBC）、中性粒细胞比例、住院时间均低于对照组2（P〈0．05）：治疗组1二氧化碳分压低于对照组1（P〈0．05）。与各对照组比较，各治疗组其余指标差异无统计学意义（P〉0．05）。各治疗组未见皮疹、腹泻等。结论：对食欲减退的AECOPD患者，复合乳酸菌可控制感染和降低住院时间．安全性好。Objective To observe the effects of lactobacillus complex capsules in patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD） and different degrees anorexia. Methods 100 anorexia score 1 and 100 anorexia score 2-5 AECOPD patients were divided into 4 groups： the therapy group 1 （anorexia score 1,n = 50） and the therapy group 2 （anorexia score 2-5,n = 50） with conventional and lactohacillus complex capsules therapy, the control group 1 （anorexia score 1, n = 50） and the control group 2 （anorexia score 2-5,n = 50） with conventional therapy. Parameters were recorded, which include length of hospital stay, markers of inflammation, arterial blood gases, lung function, clinical symptoms, death rate and side-effects of lactobacillus complex capsules. Results After treatment, WBC, trophil ratio, length of hospital stay in the therapy group 2 were lower than the control group 2（P 〈 0.05）. The PCO2 in the therapy group 1 was lower than the control group 1 （P 〈 0.05）. There were no differences in the rest parameters between the two control groups and the two therapy groups （P 〉 0.05）. No side-effects like rashes, diarrhea, were observed in the two therapy groups. Conclusion For anorexia patients with AECOPD, oral lactobacillus complex capsules can safely control infection and reduce length of hospital stay.

关 键 词：肺疾病 慢性阻塞性 治疗 食欲减退 乳酸菌 

分 类 号：R563.9[医药卫生—呼吸系统]