2010-2011年新疆生产建设兵团第八师居民肝癌疾病负担研究  

Disease burden of liver cancer of 8th Division of Xinjiang Production and Construction Crops from 2010 to 2011

作　　者：姬祥[1] 李述刚[1] 张学飞[1] 姜新华[2] 陈瑜 贾丽萍[4] 闫贻忠 徐上知[1] 

机构地区：[1]石河子大学医学院预防医学系,新疆石河子832000 [2]石河子市人民医院病案统计科,新疆石河子832000 [3]石河子市疾病预防控制中心慢病防治科,新疆石河子832000 [4]石河子大学医学院第一附属医院病案统计科,新疆石河子832000

出　　处：《中华肿瘤防治杂志》2016年第1期10-14,共5页Chinese Journal of Cancer Prevention and Treatment

基　　金：新疆生产建设兵团重大公共卫生专项(2100109)

摘　　要：目的恶性肿瘤已成为发达国家与发展中国家的主要死亡原因之一。我国恶性肿瘤死亡率逐年上升，给社会造成严重的疾病负担。本研究将了解新疆生产建设兵团第八师（简称八师）居民肝癌疾病负担情况，为制定相应防治策略和卫生规划提供科学依据。方法以2010—2011年八师肿瘤登记资料为基础，计算居民死亡率、潜在减寿年（poten—tialyears of life lost，PYLL）、伤残调整生命年（disablity adjusted life year，DALY）等指标，评价八师肝癌疾病负担。结果2010-2011年八师肝癌死亡率、中标率和世标率分别为7．57／10万、3．72／10万和4．86／10万，男性死亡率（11．58／10万）高于女性（3．50／10万）。肝癌造成的PYLL为969人年，PYLL率为8．4％；肝癌造成的DALY合计为1172．71，DALY率为1．02／千人健康生命年，伤残损失健康生命年（years lived with disability，YLD）率和死亡损失健康生命年（years lived with disability，YLL）率分别为0．04／千人和0．98／千人，男性YLL率（1．56／千人）高于女性（0．40／千人）。PYLL率与DALY率均随年龄增加而上升，45～〈50岁年龄组PYLL率及DALY率达到最高水平。结论八师居民肝癌疾病负担表现为男性高于女性，女性肝癌负担增加明显，45～〈50岁年龄组肝癌疾病负担最重。应加强肝癌的预防工作，减轻居民的肝癌疾病负担。OBJECTIVE Cancer have been the main cases in developed and developing countries. The mortality of cancer in China was increased year by year, which make serious burden for people. The objective of this study was estimate the disease burden of liver cancer among urban resident of 8th Division of Xinjiang Production and Construction Crops（XPCC） from 2010 to 2011 and provide the evidence for policy-making of disease prevention and control. METH- ODS Compute mortality rates,potential years of life lost （PYLL） ,disability adjusted life year （DALY） that based on the cancer registered data of 8th Division of XPCC from 2010 to 2011 were collected to evaluate the disease burden. RESULTS The crude mortality rate of 8th Division of XPCC 2010--2011 was 7.57/10^5 ,and the age-standardized incidence rates byChinese population and world population were 3.72/10^5 and 4.86/10^5 respectively. The mortality rate of male （11.58/ 10^5） was higher than that of female （3.50/10^5）. PYLL of liver cancer was 969 years,PYLL rate was 8.4%. The liver cancer DALY was 1 172.71 years,the DALY rate was 1.02 years per thousand capita,years lived with disability （YLD） was 0.04 years per thousand capita, years of life lost （YLL） was 0.98 years per thousand capita. YLL rate of male （1.56 years per1000） was higher than that of female（0.40 years per1000）. PYLL rate and DALY rate were gradually in- creased with age,and reached the peak at 44-〈50 age group. CONCLUSIONS The disease burden of liver cancer of 8th Division of XPCC was light. The burden of male was higher than that of female. The disease of female was increased obviously. The peak of disease burden occurred in 44-〈50 age group. Tumor prevention should be carried out so as to reduce the disease burden of liver cancer.

关 键 词：发病率 死亡率 伤残调整生命年 潜在减寿年 肝癌 疾病负担 

分 类 号：R735.7[医药卫生—肿瘤]