脑桥旁正中梗死层面数与基底动脉粥样硬化和早期进展关系  

Paramedian pontine infarction: relationship correlation between the number of slice and basilar artery atherosclerotic lesions and early progression

作　　者：田英[1,2] 辛岳[1] 王健[1] 王玉洁[1] 张碧莹[1] 

机构地区：[1]辽宁省人民医院神经内二科,辽宁沈阳110016 [2]大连医科大学神经病学系,辽宁大连116044

出　　处：《中风与神经疾病杂志》2016年第2期117-119,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的分析急性期脑桥旁正中梗死(paramedian pontine infarction,PPI)轴位弥散加权成像(diffusion weighted imaging,DWI)累及层面数与基底动脉狭窄程度及信号改变的关系,并分析与PPI引起的临床神经功能缺损早期进展的关系。方法选择经DWI确诊的脑桥旁正中梗死急性期患者96例,根据轴位DWI累及层面数,分为一层组和两层组(包括两层及两层以上)。采用MRA将基底动脉分为无狭窄、有狭窄;在T1加权像(T1weighted image,T1WI)上将基底动脉管壁分为无高信号和有高信号改变。应用美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评估临床早期病情进展。结果一层组49例(51.04%),两层组47例(48.96%),两组在基底动脉狭窄程度之间差异有统计学意义(P<0.05);两组之间基底动脉高信号改变差异有统计学意义(P<0.05);两组之间脑桥旁正中梗死临床神经功能缺损程度早期进展差异有统计学意义(P<0.05)。结论脑桥旁正中梗死轴位DWI累及层面数增多时需结合MRA与T1WI综合评估基底动脉病变情况,且要预防神经功能缺损早期进展。Objective To analysis the relationship between slice numbers of paramedian pontine infarction（ PPI）and basilar artery stenosis and early progression of neurological impairment. Methods We chose total 96 cases who were in the acute stage of paramedian pontine infarction diagnosed by diffusion weighted imaging（ DWI）. By counting involved the numbers on DWI axial view. We divided patients into one slice group and two slices group（ including more than two layers and two layers）. MRA is was used to divide the basilar artery into non stenosis,stenosis. Changes of the basilar artery on T1 weighted image（ T1WI） are were divided into non hyperintense and hyperintense. Apply National Institute of Health Stroke Scale（ NIHSS） to assess the early neurological deterioration. Results One slice group of 49 cases（ 51. 04%）,two slices group of 47 cases（ 48. 96%）,and the difference of basilar artery stenosis between the two groups is was statistically significant（ P 〈0. 05）; the difference of hyperintense between the two groups is was of statistical significance（ P〈 0. 05）; and the difference of early neurological deterioration has had statistical significance（ P〈 0. 05）. Conclusion Involving slice numbers increase on DWI axial view,we need to evaluate through MRA and T1 WI and timely prevent the early progression of neurological impairment.

关 键 词：脑桥旁正中梗死 磁共振成像 基底动脉 进展性脑卒中 

分 类 号：R743.3[医药卫生—神经病学与精神病学]