低频重复经颅磁刺激治疗96例焦虑患者的疗效分析  

Effectiveness of Low Frequency Repetitive Transcranial Magnetic Stimulation in the Treatment of 96 Anxiety Patients

作　　者：宋明桥[1] 孙亚南[1] 钟晓明[1] 李晓红[1] 

机构地区：[1]大连市友谊医院神经内科,辽宁大连116001

出　　处：《医学与哲学（B）》2016年第1期47-49,共3页Medicine & Philosophy(B)

基　　金：大连市卫计委科技自主创新与普及推广项目支持

摘　　要：近年来重复经颅磁刺激(rTMS)作为一种无创的物理方法治疗焦虑障碍的研究逐渐增多,但仍缺乏充分的证据,各治疗参数与疗效的关系也不明确。本研究分析了低频(1Hz)rTMS刺激右侧前额叶背外侧区(DLPFC)治疗96例焦虑状态患者的疗效。患者焦虑自评量表(SAS)评分明显下降,从治疗前(60.03±6.91)分降为治疗后(50.29±6.29)分,SAS评分下降程度与治疗次数及刺激强度呈正相关,而与年龄无相关性。因此,低频rTMS刺激右侧DLPFC可改善焦虑症状,疗效增强可能与治疗次数与刺激强度的增加有关。Recently the number of the studies of repetitive transcranial magnetic stimulation, a noninvasive physiotherapy, in the treatment of anxiety disorders increased gradually. However, sufficient evidence is needed. In addition, the relationship between the treatment parameters and the effectiveness is not clear. In this study, the effectiveness of low frequency （1Hz） rTMS stimulating the right dorsal lateral prefrontal cortex （DLPFC） in the treatment of 96 patients with anxiety state was analyzed. The average score of Self-Rating Anxiety Scale （SAS） decreased significantly from 60.03±6.91 before the treatment to 50.29±6.29 after the treatment. The decrease of SAS was positively correlated to the number of the treatment times and the stimuli intensity respectively. However, there was no correlation between the decrease of SAS and the patient age. In conclusion, it is possible that low frequency rTMS on the right DLPFC is effective in the anxiety patients, and enhancing the number of the treatment times and the stimuli intensity might improve the effectiveness.

关 键 词：重复经颅磁刺激 焦虑 治疗 

分 类 号：R749.72[医药卫生—神经病学与精神病学]