500例长期服用抗精神病药患者腹部超声结果分析  

Abdominal ultrasound results of 500 cases of patients with long-term use of antipsychotics

作　　者：施彦华[1] 米科睿 

机构地区：[1]乌鲁木齐市第四人民医院医技科,乌鲁木齐832002 [2]乌鲁木齐市友谊医院超声科

出　　处：《国际精神病学杂志》2016年第1期96-100,共5页Journal Of International Psychiatry

摘　　要：目的分析500例长期服用抗精神病药患者的腹部超声检查结果,为抗精神病药物的合理运用提供参考。方法选择2008年5月~2014年5月我院收治的500例长期服用抗精神病药患者行腹部B超检查,比较不同年龄、服药时间及性别的精神病患者的腹部B超检查结果。结果273例患者腹部B超检查出现异常,异常率54.6%,其中脾肿大52例,单纯脂肪肝95例,胆囊结石46例,慢性胆囊炎41例,肝脏弥漫性改变32例,其他病变7例;病程及服药时间≥6年组腹部B超异常率高于病程及服药时间〈6年组,差异有统计学意义（P〈0.05）;年龄≥60岁组腹部B超异常率高于年龄〈60岁组,差异有统计学意义（P〈0.05）;不同性别患者腹部B超异常率差异无统计学意义（P〉0.05）。结论长期服用抗精神病药的精神病患者,发生脾肿大、单纯脂肪肝、脂肪肝合并胆囊结石、脂肪肝合并胆囊息肉等异常的比例较大,病程及服药时间越长、年龄越大,发生腹部超声异常的比例越高,但与性别无关。Objective To analyse the abdominal ultrasound results of 500 cases of patients with long-termuse of antipsychotics,in order to provide a reference for reasonable use of antipsychotics. Methods From May2008 to May 2014 in our hospital,500 cases of patients with long-term use of antipsychotics were accepted abdominal ultrasound examination,and the results of type-B ultrasonic were analyzed. Results The abnormal rate of abdominal ultrasound was 54. 6%（ 273 /500）,including 52 cases of splenomegaly,95 cases of fatty liver disease,46 cases of cholecystolithiasis,41 cases of chronic cholecystitis,32 cases of diffuse liver changes,and 7 cases of other lesions. The group of patients with 6 or more years course had higher abnormal rats than that of the group of patients with less than 6 years course,the difference was statistically significant（ P〈0. 05）; The group of patients more than 60 years old had higher abnormal rate than that of the group of patients less than 60 years old,the difference was statistically significant（ P〈0. 05）; There were no statistical significance difference in abdominal ultrasound abnormality rate between different gender patients（ P〉0. 05）. Conclusion The patients with long-term use of antipsychotic medecines have high rate of splenomegaly,simple fatty liver,fatty liver merger gallstones,fatty liver,gallbladder polyp and other abmormity,the course of the disease,treatment time and age were the risk factors of abnormal results of abdominal ultrasound.

关 键 词：抗精神病药物 腹部B超 

分 类 号：R749.05[医药卫生—神经病学与精神病学]