普鲁士蓝纳米粒子在生物医学诊断和治疗中的应用及进展  

The Application and Progress of Prussian Blue in Biomedical Diagnosis and Therapy

作　　者：刘伟[1] 胡乐婧 林丽[1] 刘爱龙[1] 冯珊珊[1] 

机构地区：[1]哈尔滨工业大学生命科学与技术学院,黑龙江哈尔滨150080

出　　处：《现代生物医学进展》2016年第1期176-178,共3页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(21273014)

摘　　要：随着生物医学诊断和治疗的持续深入研究,出现了多种医学诊断和治疗新方法,为人类的健康提供了更大的保证,其中纳米生物技术在生物医学诊断和治疗中的应用日益增多,基于纳米技术,开发传统材料的生物医学新应用成为了人们的研究热点。普鲁士蓝是一种历史悠久的蓝色染料,其制备过程简单、绿色、成本低,化学结构稳定,具有优良的物理、化学、光学以及磁性等性能,已经在许多领域得到了广泛的应用。近年来,普鲁士蓝开始在生物医学诊断和治疗领域中崭露头角,它已经成功的被开发为新型的核磁共振造影剂和光声成像造影剂,并且在药物输送系统和光热治疗等领域也开始占有一席之地,开发基于纳米技术的普鲁士蓝的生物医学应用已经成为极具吸引力的研究方向。本文对普鲁士蓝在生物医学诊断和治疗中的应用及进展进行综述。With the continuing development of biomedical diagnosis and therapy, a variety of new medical diagnosis and therapy methods have been established for providing greater guarantee of human health, among these methods, the application of nano-biotechnology in biomedical diagnosis and therapy plays an increasing role in our society, the research of developing new biomedical applications of traditional materials based on nanotechnology has become a new hotspot. Prussian blue is an ancient cheap blue dye which can be prepared easily. It has been widely used in many fields due to its advantages including outstanding stability, excellent physical, chemical, optical and magnetic properties. In recent years, Prussian blue has come into prominence in the field of biomedical diagnosis and therapy. It has been developed as a new type of nuclear magnetic resonance imaging contrast agent and photoacoustic tomography contrast agent successfully, and it also has been applied in drug delivery system and photothermal therapy. The application of Prussian blue nanoparticles in biomedical field has become an attractive research direction. This paper reviewed the application and progress of Prussian blue in biomedical diagnosis and therapy fields.

关 键 词：普鲁士蓝 生物医学诊断 生物医学治疗 纳米生物技术 

分 类 号：R-332[医药卫生] R318