精神分裂患者医院感染相关因素分析  

Related factors for nosocomial infections in patients with schizophrenia and control programs

作　　者：袁朝霞[1] 章秋萍[1] 朱小英[1] 张丽英[1] 张蕾[1] 方芳[1] 

机构地区：[1]杭州市第七人民医院精神科,浙江杭州310013

出　　处：《中华医院感染学杂志》2016年第5期1189-1191,共3页Chinese Journal of Nosocomiology

基　　金：浙江省医药卫生计划基金资助项目(2013KYB065)

摘　　要：目的探讨精神分裂患者医院感染的主要原因及控制方案,为临床预防与控制医院感染提供参考依据。方法分析医院2012年1月-2014年12月收治的550例精神分裂患者临床资料,对其中发生医院感染患者的相关因素进行分析,并制定有效的预防措施。结果 550例患者中91例发生医院感染,感染率16.55%,男性感染率为16.62%,女性感染率为14.23%,男性患者感染率明显高于女性患者,差异有统计学意义(P<0.05);60岁以上患者感染率38.46%,显著高于其他年龄段人群,差异有统计学意义,(P<0.05);在服用抗精神分裂药物剂量>600mg时患者感染率最高,为37.50%;精神分裂患者中偏执型发生医院感染率40.65%,远高于其他类型患者;患者住院时间>12个月感染率高达37.78%;患有呼吸道疾病的患者发生感染率57.14%,高于患有其他基础疾病的患者。结论精神分裂病患者发生医院感染的影响因素较多,应针对性制定相应的预防性措施。OBJECTIVE To explore the major causes of nosocomial infections in patients with schizophrenia and put forward the control programs so as to provide guidance for clinical prevention and control of nosocomial infections.METHODS The clinical data of 550 patients with schizophrenia who were treated in the hospital from Jan 2012 to Dec 2014 were analyzed,the related factors for the nosocomial infections were analyzed,and the effective prevention measures were formulated.RESULTS Of the 550 patients,91had nosocomial infections with the infection rate of 16.55%,the infection rate of the male patients was 16.62%,significantly higher than 14.23% of the female patients（P〈0.05）;the infection rate of the patients aged more than 60 years old,significantly higher than that of other age groups of patients（P〈0.05）.The infection rate was the highest（37.50%）in the patients who were treated with more than 600 mg dose of antipsychotics.The infection rate of the patients with paranoid schizophrenia was 40.65%,significantly higher than that of the patients with other types of schizophrenia.The infection rate of the patients with the length of hospital stay more than 12 weeks was as high as 37.78%.The case-time infection rate of the patients with respiratory tract diseases was 57.14%,higher than that of the patients with other underlying diseases.CONCLUSIONThere are a variety of influencing factors for the nosocomial infections in the patients with schizophrenia.It is necessary to formulate the corresponding prevention measures.

关 键 词：医院感染 精神分裂 患者 控制方案 

分 类 号：R749.3[医药卫生—神经病学与精神病学]