Evaluation of corneal endothelium after UVA/riboflavin cross-linking in thin keratoconic corneas  

作　　者：Wei Chen Zhi-Wei Li Xiao-Min Zhao Wen -Wen Xu Guo-Ying Mu 

机构地区：[1]Clinical College of Ophthalmology, Tianjin Medical University [2]Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong University [3]School of Nursing, Binzhou Medical College

出　　处：《International Journal of Ophthalmology(English edition)》2016年第2期321-322,共2页国际眼科杂志（英文版）

摘　　要：Dear Sir,UVA/riboflavin cross-linking （CXL） has been used clinically applied for the treatment of keratoconus and corneal edema via enhancement of corneal stiffness The safety of the corneal endothelium is of prime importance during CXL treatment. In clinical practice, a corneal thickness （CT） of 400um has traditionally been regarded as the minimum treatable thickness, thereby avoiding damage to the corneal endothelium Although CXL has been applied to thinner corneas, using a hypoosmotic solution onto cornea and inducing edema . CXL safety still needs further evaluation because of lower relative concentration of collagen in the hydrated stroma . This study aims to evaluate the changes of corneal endothelial density （ECD） in cases where the CT is 〈400 um before iatrogenic corneal swelling and CXL treatment.Dear Sir,UVA/riboflavin cross-linking （CXL） has been used clinically applied for the treatment of keratoconus and corneal edema via enhancement of corneal stiffness The safety of the corneal endothelium is of prime importance during CXL treatment. In clinical practice, a corneal thickness （CT） of 400um has traditionally been regarded as the minimum treatable thickness, thereby avoiding damage to the corneal endothelium Although CXL has been applied to thinner corneas, using a hypoosmotic solution onto cornea and inducing edema . CXL safety still needs further evaluation because of lower relative concentration of collagen in the hydrated stroma . This study aims to evaluate the changes of corneal endothelial density （ECD） in cases where the CT is 〈400 um before iatrogenic corneal swelling and CXL treatment.

关 键 词：UVA Evaluation of corneal endothelium after UVA/riboflavin cross-linking in thin keratoconic corneas 

分 类 号：R772.2[医药卫生—眼科]