血栓弹力图评价不同程度肝硬化患者凝血功能价值  被引量:22

Value of thromboelastography to evaluating coagulation abnormalities in patients with hepatic cirrhosis in different degrees

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作  者:曾艳丽[1] 靳秀[1] 高飞[1] 王茹真[1] 侯环荣[1] 魏君锋[1] 尚佳[1] 康谊[1] 

机构地区:[1]郑州大学人民医院河南省人民医院感染科,郑州450003

出  处:《中华实用诊断与治疗杂志》2016年第3期254-256,共3页Journal of Chinese Practical Diagnosis and Therapy

基  金:河南省科技厅基础与前沿技术研究项目(142300410372);河南省医学科技攻关计划省部共建项目(201301009);河南省医学科技攻关项目(201303120)

摘  要:目的分析肝硬化不同肝功能分级患者血栓弹力图(thromboelastography,TEG)表现。方法肝硬化患者107例,肝功能Child A级36例为Child A级组,Child B级38例为Child B级组,Child C级33例为Child C级组,监测3组TEG并比较分析。结果 Child C级组TEG中R值[(6.20±1.88)min]、K值[(4.10±2.03)min]高于Child A级组[(4.45±1.21)、(2.37±1.58)min]和Child B级组[(5.12±1.56)、(3.25±1.02)min],LY30(0)、MA[(25.20±6.51)mm]和Angle[(41.42±10.27)deg)]低于Child A级组[(0.80±0.11)%、(59.30±7.30)mm、(62.67±10.20)deg]和Child B级组[(0.60±0.17)%、(36.80±5.84)mm、(50.87±9.68)deg],差异均有统计学意义(P<0.05)。结论 TEG可反映肝硬化患者凝血紊乱状况,TEG参数异常间接反映了病情严重程度。Objective To analyze the thromboelastogram performances in hepatic cirrhosis patients with different hepatic function. Methods In 107 patients with hepatic cirrhosis included 36 patients with hepatic function Child A (Child A group), 38 with Child B (Child B group) and 33 with Child C (Child C group). Thromboelastography was performed and the results were compared among three groups. Results R value ((6.20±1.88) rain) and K value ((4.10±2.03) min) in Child A group were significantly higher than those in Child C group ((4.45±1.21), (2.37±1.58) rain) and Child B group ((5. 12±1. 56), (3. 254±1. 02) min) (P〈0.05). While LY30 (0), MA ((25. 20±6. 51) ram) and Angle ((41.42±10.27) deg) in Child C group were significantly lower than those in Child A group ((0. 80± 0. 11)%, (59.30±7.30) mm, (62. 67±10.20) deg) and Child B group ((0.604±0.17)%, (36.80±5.84) ram, (50. 87±9.68) deg) (P〈0.05). Conclusion Thromboelastography could reflect the blood coagulation state in patients with hepatic cirrhosis and it is correlated with the severity of hepatic cirrhosis.

关 键 词:肝硬化 血栓弹力图 凝血 CHILD分级 

分 类 号:R575.2[医药卫生—消化系统]

 

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