肢体恶性骨肿瘤治疗研究进展  

Progress in the treatment of malignant limb tumors

作　　者：欧阳龙[1] 尹东[2] 彭昊[1] 

机构地区：[1]武汉大学人民医院骨科,430000 [2]广西壮族自治区人民医院骨科

出　　处：《临床外科杂志》2016年第2期141-143,共3页Journal of Clinical Surgery

摘　　要：肢体恶性骨肿瘤是一组死亡率较高的疾病,随着分子生物学及组织生物工程学的发展,其治疗方法也取得了很大的进展,尤其是保肢综合治疗的发展,明显提高了恶性瘤患者的5年生存率,并且提高了患者术后的生活质量。本文从传统的截肢术到新辅助化疗支持下的保肢治疗、免疫治疗、基因治疗、靶向治疗等方面作一个系统的综述,对肢体恶性骨肿瘤的临床治疗提供参考。Malignant limb tumor is a disease with high mortality rate. With the development of molecular biology and tissue bioengineering, the treatment of malignant limb tumor achieves great progress, especially in the comprehensive treatment for limb salvage. It significantly improves the 5-year survival rate and postoperative quality of life in patients with malignant tumors. This paper reviewed tradition- al amputation surgery,limb salvage surgery, neo-adjuvant chemotherapy, immunotherapy, gene therapy, and targeted therapy systematically, which provided references for the clinical treatment of malignant limb tumors.

关 键 词：肢体恶性骨肿瘤 治疗 研究进展 

分 类 号：R738.1[医药卫生—肿瘤]