鼻内翻性乳头状瘤恶变与人乳头状瘤病毒相关性  

Research progress of relationship between SNIP malignancy and HPV infection

作　　者：周恩晖 陈晓平[2] 姚文吴 滕伟强[1] 孙璞[3] 

机构地区：[1]宁夏医科大学耳鼻咽喉专业,银川750004 [2]上海市浦东新区公利医院耳鼻咽喉科,200135 [3]天津市第四中心医院耳鼻咽喉科,300143

出　　处：《国际耳鼻咽喉头颈外科杂志》2016年第2期109-112,共4页International Journal of Otolaryngology-Head and Neck Surgery

基　　金：浦东新区科学发展资金创新基金（PKJ2012-Y27）和上海市浦东新区重点学科群（PWZxq2014-09）项目联合资助

摘　　要：鼻内翻性乳头状瘤（sinonasal inverted papilloma，SNIP）是鼻腔及鼻窦较常见的良性肿瘤，但具有侵袭破坏性、易复发性以及恶变倾向，严重危害患者的健康。人乳头状瘤病毒（human papillomavirus，HPV）感染在SNIP的发生、发展及转归过程中发挥着重要作用，尤其是逐步认识到某些亚型HPV感染可能与SNIP恶变存在相关性。因此对HPV生物学特性及临床特性的深入研究认识有助于提高对SNIP的诊断、治疗及预防水平。本文就HPV与SNIP恶变的相关性研究进展做一综述。Although sinonasal inverted papilloma （SNIP） is a common benign tumor which usually occurs in nose and paranasal sinus, it has a trend of attacking, recurrence and malignancy. Human papillomavirus （HPV） infection plays an important role in SNIP development. Subtypes of HPV may have close relation to SNIP malignancy has been regularly realized. An in-depth research in biological and clinical character of HPV will improve the diagnosis, treatment and prevention of SNIP. This review is about the researching progress of relationship between SNIP malignancy and HPV infection.

关 键 词：乳头状瘤 内翻 乳头状瘤病毒感染 

分 类 号：R739.62[医药卫生—肿瘤]