血管危险因素与阿尔茨海默病关系的研究进展  

Progress on Relationship Between Vascular Risk Factors and Alzheimer's Disease

作　　者：闫超群[1] 刘艺[1] 林丽婷[1] 石广霞[2] 杨静雯[2] 刘存志[2] 

机构地区：[1]天津中医药大学研究生院,天津市300193 [2]首都医科大学附属北京中医医院针灸中心

出　　处：《实用心脑肺血管病杂志》2016年第2期1-4,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：国家自然科学基金面上项目(81473501);北京市科技计划课题"首都临床特色应用研究"专项(Z131107002213034);北京市科学技术委员会首都市民健康项目培育课题(Z1311000068132002)

摘　　要：随着我国人口老龄化进程加剧,阿尔茨海默病(AD)发病率呈逐年增高趋势。目前,AD的确切病因尚未明确,其病理机制复杂,且缺乏有效的治疗措施。世界卫生组织(WHO)强调,早期预防在降低AD发病率中起关键作用。有研究表明,血管危险因素(如高血压、糖尿病、心脏疾病等)可导致认知功能减退,增加AD发病风险。因此,了解血管危险因素与认知障碍的关系有助于阻断或延缓认知障碍向AD发展。本文就血管危险因素与AD关系的研究进展进行综述。As the aggravation of population aging process in China,the morbidity of Alzheimer＇s disease increased year by year. At present, the definite etiological factor of Alzheimer＇ s disease is still not clear, but its pathomechanism is complex,and there is a less of effective treatment so far. WHO once emphasized that early prevention play a key role in reducing the morbidity of Alzheimer＇ s disease. Vascular risk factors（ such as hypertension,diabetes and heart disease） may result in cognitive decrease and increase the onset risk of Alzheimer＇ s disease. Acquaintance of relationship between vascular risk factors and cognitive disorder is helpful to interdict or delay the process to Alzheimer＇ s disease. This paper reviewed the progress on relationship between vascular risk factors and Alzheimer＇s disease.

关 键 词：阿尔茨海默病 血管 危险因素 综述 

分 类 号：R745.7[医药卫生—神经病学与精神病学]