接骨灵贴膏质量标准的研究  

Quality standard for Jieguling Emplastrum

作　　者：袁杰 刘道芳[2] 

机构地区：[1]安徽省食品药品检验研究院,安徽合肥230051 [2]安徽安科余良卿药业有限公司,安徽合肥230088

出　　处：《中成药》2016年第3期575-578,共4页Chinese Traditional Patent Medicine

摘　　要：目的建立接骨灵贴膏(当归、骨碎补、续断等)的质量标准。方法 TLC法对接骨灵贴膏中的当归进行定性鉴别;GC法对其中冰片、樟脑、桉油精和水杨酸甲酯的含有量进行测定。结果薄层色谱斑点清晰分离度良好,无阴性干扰。冰片、樟脑、桉油精和水杨酸甲酯的回收率(n=6)分别为96.7%(RSD=3.1%)、96.8%(RSD=1.3%)、96.4%(RSD=1.6%)和98.4%(RSD=1.4%)。结论 TLC法和GC法能有效监控接骨灵贴膏的质量。AIM To establish a quality standard for Jieguling Emplastrum（ Angelicae Sinensis Radix,Drynariae Rhizoma,Dipsaci Radix,etc.）. METHODS A. Sinensis in Jieguling Emplastrum was identified by TLC.The contents of borneol,camphor,cineol and methyl salicylate in this preparation were determined by GC. RESULTS The clear TLC spots showed good resolution without interference from negative samples. The average recoveries（ n = 6） of borneol,camphor,cineol and methyl salicylate were 96. 7%（ RSD = 3. 1%）,96. 8%（ RSD = 1. 3%）,96. 4%（ RSD = 1. 6%） and 98. 4%（ RSD = 1. 4%）,respectively. CONCLUSION TLC and GC can be applied to monitoring the quality of Jieguling Emplastrum.

关 键 词：接骨灵贴膏 当归 冰片 樟脑 桉油精 水杨酸甲酯 TLC GC 

分 类 号：R927.2[医药卫生—药学]