成人骨性Ⅱ类错牙合畸形患者血清碱性磷酸酶浓度的初步研究  

Serum alkaline phosphatases concentration in adult patients with skeleton class Ⅱ malocclusion: preliminary results

作　　者：马艳[1] 施优灵[2] 李金超[2] 刘继光[3] 

机构地区：[1]湖北医药学院附属东风医院口腔医院口腔正畸科,湖北十堰442008 [2]湖北医药学院附属东风医院口腔医院口腔颌面外科,湖北十堰442008 [3]佳木斯大学研究生院,黑龙江佳木斯154007

出　　处：《口腔医学》2016年第3期244-247,共4页Stomatology

摘　　要：目的研究骨性Ⅱ类错牙合畸形患者的血清碱性磷酸酶浓度及意义。方法选择45例成人骨性Ⅱ类错牙合畸形患者和47例年龄和性别匹配的正常对照成人,检测其血清碱性磷酸酶浓度。应用SPSS 18.0软件对检测值进行成组t检验统计学分析。结果成人骨性Ⅱ类错牙合畸形患者和正常对照成人的血清ALP浓度分别为(41.62±1.97)U/L和(65.83±2.70)U/L。其中男性骨性Ⅱ类错牙合畸形患者和对照成人的血清ALP浓度分别为(52.07±4.63)U/L和(68.25±2.65)U/L,女性分别为(36.40±0.92)U/L和(64.04±4.28)U/L。25岁以下骨性Ⅱ类错牙合畸形患者和对照成人的血清ALP浓度分别为(42.15±3.28)U/L和(65.43±4.64)U/L,其中男性分别为(52.75±18.55)U/L和(69.67±10.67)U/L,女性分别为(34.40±3.92)U/L和(62.10±18.50)U/L。大于25岁骨性Ⅱ类错牙合畸形患者和对照成人分别为(41.20±2.45)U/L和(66.00±3.35)U/L,其中男性分别为(51.29±18.68)U/L和(66.88±11.76)U/L,女性分别为(37.28±5.56)U/L和(65.18±24.68)U/L。不同年龄、不同性别及总体人群骨性Ⅱ类错牙合畸形患者和对照成人的血清ALP浓度差异均具有统计学意义(P<0.05)。结论骨性Ⅱ类错牙合畸形患者的血清ALP浓度较正常对照成人低,提示骨性Ⅱ类错牙合畸形患者的骨代谢较弱,可能与下颌骨发育不足有关。Objective To explore the concentration and roles of serum alkaline phosphatases（ ALP） in patients with skeleton class II malocclusion. Methods 45 adult patients with skeleton class II malocclusion and 47 age-and sex-matched healthy controls were selected in this study,and the concentrations of serum ALP were collected. The difference between experimental and control groups was assessed by independent Student＇s t-test with SPSS 18. 0 software. Results The serum ALP level in patients and that in healthy controls were（ 41. 62 ± 1. 97） U / L and（ 65. 83 ± 2. 70） U / L,respectively. The serum ALP level in male patients and that in healthy controls were（ 52. 07 ± 4. 63） U / L and（ 68. 25 ± 2. 65） U / L,whereas that in female patients and that in healthy controls were（ 36. 40 ±0. 92） U / L and（ 64. 04 ± 4. 28） U / L,respectively. The serum ALP level in patients 〈25 years old and that in healthy controls were（ 42. 15 ± 3. 28） U/L and（ 65. 43 ± 4. 64） U/L,among which,male patients vs. healthy controls was（ 52. 75 ± 18. 55） U/L vs.（ 69.67 ± 10. 67） U / L,and female patients vs. healthy controls was（ 34. 40 ± 3. 92） U / L vs.（ 62. 10 ± 18. 50） U / L. Further,the serum ALP level in patients 25 years old vs. that in healthy controls was（ 41. 20 ± 2. 45） U / L vs.（ 66. 00 ± 3. 35） U / L,and（ 51. 29 ± 18.68） U / L vs.（ 66. 88 ± 11. 76） U / L for males,while（ 37. 28 ± 5. 56） U / L vs（ 65. 18 ± 24. 68） U / L for females. The significant statistical difference was observed（ P〈0. 05）. Conclusion The serum ALP level in adult patients with skeleton class II malocclusion is lower than that in healthy controls,suggesting weaker bone metabolism in the patients,which may be resulted from mandibular hypodevelopment.

关 键 词：骨性 Ⅱ类错牙合 血清碱性磷酸酶 

分 类 号：R783.5[医药卫生—口腔医学]