双黄连注射液对肺炎小儿血清CRP、降钙素原及IL-6水平的影响  

Effect of Shuanghuanglian injection on CRP,PCT and IL-6 in pneumonia children

作　　者：程灏[1] 丁国标[1] 王兴[1] 黎海燕[1] 

机构地区：[1]江西省九江市妇幼保健院儿科,江西九江332000

出　　处：《中国生化药物杂志》2015年第12期133-135,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探究双黄连注射液对肺炎小儿血清C反应蛋白(C reactive protein,CRP)、降钙素原(procalcitonin,PCT)及白细胞介素-6(interleukin-6,IL-6)水平影响研究。方法收集肺炎患儿68例,根据治疗方法不同分为对照组和治疗组,其中治疗组35例,对照组33例,2组均实施常规对症治疗以及抗感染治疗,对照组应用头孢噻肟钠注射液,治疗组在此基础上应用双黄连注射液治疗,治疗结束后对比分析2组患者血清CRP、降钙素原及IL-6水平。结果治疗后与对照组相比,治疗组患者的血清CRP水平较低(P<0.05),血清降钙素原水平较低(P<0.05),治疗组患者的IL-6水平较低(P<0.05)。结论双黄连注射剂对小儿肺炎具有较好的疗效,推测其机制与降低血清CRP、降钙素原及IL-6水平有关。Objective To study the effect of Shuanghuanglian injection on CRP,PCT and IL-6 in pneumonia children. Methods 68 cases of pneumonia children were selected and divided into the control group and the experiment group. 33 case in the control group and 35 cases in the experiment group. The two groups were treated with conventional symptomatic treatment and anti infection treatment for the two groups were implemented routine symptomatic treatment and anti infection treatment. The control group were treated with cefotaxime sodium injection,the experiment group were treated on the base with Shuanghuanglian injection. CRP,PCT and IL-6 in serum were compared before and after the treatment. Results Compared with the control group,the level of CRP in serum was lower（ P〈0. 05）,the level of PCT in serum was lower（ P〈0. 05）,the level of IL-6 in serum was lower（ P〈0. 05）. Conclusion Shuanghuanglian injection has a good clinical effect on children＇s pneumonia. It is speculated that the mechanism is related to the decrease of serum CRP and IL-6 level.

关 键 词：双黄连注射液 肺炎小儿 C反应蛋白 降钙素原 白细胞介素-6 

分 类 号：B725.7[哲学宗教—外国哲学]