牛链球菌在瘤胃中产酸的代谢机制及调控  

Metabolic Mechanism of Acid Production by Streptococcus bovis in Rumen and Its Regulation

作　　者：陈连民[1] 沈宜钊 王洪荣[1] 

机构地区：[1]扬州大学动物科学与技术学院,扬州225009

出　　处：《动物营养学报》2016年第3期665-673,共9页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：江苏省研究生实践创新计划(SJLX15_0674);国家自然科学基金(31572429);公益性行业(农业)科研专项(201303144);江苏省优势学科建设项目(PADA)

摘　　要：牛链球菌(S.bovis)是瘤胃主要的乳酸产生菌,在饲喂高精料饲粮导致瘤胃乳酸中毒进程中扮演重要角色。已有研究证实S.bovis利用碳水化合物代谢产酸主要受葡萄糖转运方式、酵解产酸途径中酶和中间代谢物调控。另外,研究也发现环境p H、增殖生长阶段及分解代谢控制蛋白(Ccp A)等对其产酸速率和模式也有显著影响。本文对近年来有关S.bovis利用饲料中碳水化合物发酵产酸代谢途径及影响因素研究加以综述,为从微生物代谢角度解析瘤胃乳酸中毒机制提供参考。Streptococcus bovis（ S. bovis） is usually a major lactate producing bacterium in the rumen,and is recognized its＇ contribution to development of rumen acidosis when ruminants are fed high concentrate diets.Previous work indicates that carbohydrate metabolism in S. bovis is mainly affected by the way of glucose trans membrane transport,and enzymes and intermediate metabolites in glycolytic pathway. In addition,the factors,environmental p H,growth stage,and control protein catabolism（ Ccp A）,etc.,also have significant impacts.In this paper,metabolic mechanism and influence factors of carbohydrate fermentation and acid production by S.bovis were reviewed in purpose to provide references for further insight into the mechanism of rumen acidosis caused by lactic acids.

关 键 词：牛链球菌 乳酸 瘤胃酸中毒 代谢途径 

分 类 号：S852.2[农业科学—基础兽医学] S823[农业科学—兽医学]