EB病毒相关胃癌的研究进展  

Research progress of Epstein-Barr virus-associated gastriccarcinoma

作　　者：梁垚[1] 周志伟[1] 

机构地区：[1]中山大学肿瘤防治中心胃胰科,广州510060

出　　处：《中华胃肠外科杂志》2016年第3期355-360,共6页Chinese Journal of Gastrointestinal Surgery

摘　　要：EB病毒相关胃癌（EBVaGC）在全球胃癌病例中占近10％，其具有独特的临床病理学特性，包括以男性为主、早期常可见“花边图型”的特征性改变、较少淋巴结转移以及大量、多样的炎性细胞浸润。EBVaGC的诊断金标准为EBER．ISH检测。由于对其认识有限，目前EBVaGC尚无特殊的治疗方法，但其预后相对较好。本文介绍了EBV和胃癌的关系以及EBVaGC的流行病学和临床特征．并对其临床诊断、治疗和预后的现状进行简要探讨。Epstein-Barr virus-associated gastric carcinoma （EBVaGC） comprises nearly 10% of gastric carcinoma in the world. EBVaGC is supposed to have distinct elinicopathologieal features, including male predominance, the ＇lace pattern＇ in the early stage, lower rate of lymph node involvement and infiltration of a large number of various inflammatory cells. EBER-ISH detection is the golden standardin the diagnosis of EBVaGC. Although there is no special therapy due to the limited understanding, EBVaGC has a better prognosis. In this paper, the relationship of EBV with gastric carcinoma, the epidemiological and clinical features of EBVaGC will be briefly introduced. In addition, the clinical diagnosis, treatment, and the prognosis of the status quo will be discusse＆

关 键 词：EB病毒 胃肿瘤 研究进展 

分 类 号：R735.2[医药卫生—肿瘤]