经鼻孔蝶窦入路神经内镜下垂体瘤切除术对老年垂体瘤患者预后的影响  

The prognosis influence of pituitary tumor resection by nostril transsphenoidal approach with endo-scopic in the elderly patients with pituitary tumor

作　　者：周凯[1] 张庭荣[1] 范雁东[1] 赛力克[1] 杜郭佳[1] 吴鹏飞[1] 更.党木仁加甫[1] 

机构地区：[1]新疆医科大学第一附属医院神经外科,乌鲁木齐830054

出　　处：《中国医学前沿杂志（电子版）》2016年第2期18-20,共3页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

基　　金：国家自然科学基金(81160150);新疆自治区自然科学基金(2013211A078)

摘　　要：目的探究经鼻孔蝶窦入路神经内镜下垂体瘤切除术对老年垂体瘤患者预后的影响。方法选取2011年5月至2014年5月本院收治的老年垂体瘤患者104例为研究对象,将其随机分为观察组和对照组,入院后均予以常规处理,观察组患者在神经内镜下行垂体瘤切除术,对照组患者在显微镜下行垂体瘤切除术。随访1年,比较两组患者围术期情况、术后并发症发生情况及预后。结果观察组患者手术时间、术中出血量、术后住院时间均明显少于对照组(P<0.05)。两组患者并发症总发生率比较差异具有显著性(P<0.05)。术后6个月观察组患者临床表现改善率为79.2%,对照组为64.0%;术后1年观察组患者临床表现改善率为93.8%,对照组为72.0%;差异均具有显著性(P<0.05)。结论经鼻孔蝶窦入路神经内镜下垂体瘤切除术对老年垂体瘤患者疗效显著,且并发症少,预后良好,值得临床推广应用。Objective To explore the prognosis influence of pituitary tumor resection by nostril transsphenoidal approach with endoscopic in the elderly patients with pituitary tumor. Method Selected 92 cases of pituitary tumor patients accepted by our hospital from May 2011 to May 2014, they were divided into observation group and control group randomly. Conventional therapy were took on both groups, pituitary adenoma resection by descends endoscopic were used for observation group and pituitary adenoma resection by microscope downside were used for control group. Two groups of patients were followed up for 12 months, the perioperative indexes, postoperative complications and prognosis were observed between the two groups. Result The operation time, intraoperative blood loss, postoperative hospitalization days of observation group were less than control group（P〈0.05）. There were significant differences in the incidence of complications between the two groups（P〈0.05）. The clinical symptoms improved rate of two groups in 6 months after operation were 79.2% and 64.0%, and the rate of two groups in 1 year after operation were 93.8% and 72.0% respectively, the results were statistically significant（P〈0.05）. Conclusion Pituitary tumor resection by nostril transsphenoidal approach with endoscopic in the elderly patients with pituitary tumor has a good effect, with fewer complications and better prognosis. It is worthy of clinical promotion.

关 键 词：神经内镜 垂体瘤 预后 老年 

分 类 号：R736.4[医药卫生—肿瘤]