糖尿病性黄斑水肿的频域OCT与FFA对比分析  

Characters of diabetic macular edema in frequency-domain optical coherence tomography and fundus fluorescein angiography

作　　者：田洁[1] 王翠丽[1] 扈月平[1] 张戈非[1] 

机构地区：[1]大连市友谊医院眼科,辽宁大连116001

出　　处：《中国现代医生》2016年第5期73-75,F0003,共4页China Modern Doctor

摘　　要：目的分析糖尿病性黄斑水肿（DME）的频域OCT及眼底荧光血管造影（FFA）特点。方法选择2014年3月~2015年10月在我院经FFA确诊为糖尿病视网膜病变（DR）的患者30例54只眼为研究对象,回顾性分析其Cirrus HD-OCT黄斑容积512×128扫描和FFA特点。结果 OCT显示37只眼（68.5%）外核层/外丛状层弥漫性水肿,10只眼（18.5%）内核层囊样水肿。FFA显示29只眼（53.7%）黄斑弥漫性水肿,14只眼（25.9%）局限性水肿,5只眼（9.3%）囊样水肿。其中,44只眼（81.5%）两者均显示ME,3只眼（5.6%）仅OCT显示ME,4只眼（7.4%）仅FFA显示ME,3只眼（5.6%）两者均未显示ME。经配对χ~2检验,差异无统计学意义（P=1.000〉0.05）。结论在诊断和治疗DME过程中,OCT和FFA互为补充,可以联合使用。Objective To study characters of diabetic macular edema（DME） in frequency-domain OCT and fundus fluorescein angiography（FFA）. Methods A total of 54 eyes of 30 patients in hospital from March 2014 to October 2015 after the diagnosis of diabetic retinopathy by FFA were examined by Cirrus HD-OCT macular volume 512 ×128 scans.Characters of them in OCT and FFA were analyzed retrospectively. Results In OCT diffuse edema in outer nuclear layer/outer plexiform layer was present in 37 eyes（68.5%）, while cystoid edema in inner nuclear layer in 10 eyes（18.5%）. In FFA diffuse edema was present in 29 eyes（53.7%）, while focal edema in 14 eyes（25.9%） and cystoid edema in 5 eyes（9.3%）. Macular edema was found by both of them in 44 eyes（81.5%）, only by OCT in 3 eyes（5.6%）, only by FFA in 4eyes（7.4%）, and by neither of them in 3 eyes（5.6%）. By Mc Nemar Test, the differences were not ststistically significant（P=1.000〉0.05）. Conclusion During the diagnosis and remedy of DME, OCT and FFA are supplemented each other and combined to use.

关 键 词：糖尿病视网膜病变 糖尿病性黄斑水肿 黄斑水肿 光学相干断层扫描 眼底荧光血管造影 

分 类 号：R774.5[医药卫生—眼科]