散发性肾血管母细胞瘤临床病理观察  

Sporadic intravascular large B cell lymphoma: a case report and review of literature

作　　者：卫惠杰[1] 任俊伟[2] 刘定荣[1] 吴彤[1] 刘凤[1] 

机构地区：[1]重庆市涪陵中心医院病理科,四川涪陵408000 [2]重庆市涪陵中心医院神经内科,四川涪陵408000

出　　处：《诊断病理学杂志》2016年第3期169-171,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨散发性肾血管母细胞瘤的临床病理特征、免疫表型、诊断与鉴别诊断。方法对1例原发性肾血管母细胞瘤进行组织学观察、免疫组化染色检测和临床随访,并复习相关文献。结果组织学形态显示肿瘤由2种成分构成:即不同成熟阶段的毛细血管和毛细血管网之间丰富的间质细胞。免疫组化:肿瘤间质细胞特征性地呈现α-Inhibin、vimentin、NSE和S-100(+),毛细血管壁CD34(+)。特殊染色显示苏丹Ⅲ(-)。结论散发性肾血管母细胞瘤是一种极少见的肿瘤,属于肾良性间叶性肿瘤,组织病理学特点结合免疫组化标记有助于该瘤的确诊。Objective To investigate the clinicopathological characteristics of sporadic renal hemangiohlastoma.Methods One case of sporadic renal hemangiohlastoma was studied by microscopic observation,immunohistochemical staining and the clinical follow-up. Sporadic renal hemangiohlastoma reported in the literature were reviewed. Results The characteristic histological patterns of the tumor included two major components： capillary and stromal cells.Immunohistochemistry showed that the tumor stromal cells characteristicly expressed α-Inhibin,vimentin,NSE and S-100 protein. The endothelial cells were positive for CD34. Special staining was negative for Sudan Ⅲ. Conclusion Sporadic renal hemangiohlastoma is a rare benign neoplasm. Pathological characteristics combined with immunohistochemistry is important in the final confirmation of the tumor diagnosis.

关 键 词：血管母细胞瘤 肾 免疫组化 

分 类 号：R737.1[医药卫生—肿瘤]