PET/CT在乳腺癌疗效监测中的作用  

The role of PET/CT in monitering the treatment effect of breast cancer

作　　者：郭粹[1] 陈虞梅[1] 童林军[1] 刘建军[1] 黄钢[1] 

机构地区：[1]上海市交通大学医学院附属仁济医院核医学科,上海200127

出　　处：《国际医学放射学杂志》2016年第2期146-150,161,共6页International Journal of Medical Radiology

摘　　要：18F-FDG PET集合了形态学与功能学成像的优势,可通过观察肿瘤细胞内FDG的浓聚程度变化来评价药物治疗的效果,因此在乳腺癌新辅助化疗(NAC)及复发/转移性乳腺癌的综合治疗中颇受关注。本文就18FFDG PET/CT在乳腺癌NAC及复发/转移性乳腺癌治疗中的作用进行总结,同时对近期较受关注的新型显像方式,如雌激素受体显像、细胞乏氧显像、细胞增殖显像、Her-2/neu显像等在乳腺癌中的应用进行归纳及展望。Fluoine-18 fluorodeoxyglucose positron emission tomography（18F-FDG PET） combines the advantage of morphological and functional imaging. It can be used to evaluate effects of cancer therapy by observing the changes of the FDG uptake degree.18F-FDG PET has gained increasing popularity in neoadjuvant chemotherapy and in the comprehensive treatment of reccurent/metastatic breast cancer. In this review we focused on the role of18F-FDG PET（PET/CT） in neoadjuvant chemotherapy of primary breast cancer and the treatment of recurrent and metastatic breast cancer. Furthermore,we made a summary and outlook of the other new appearing agents which have attracted increasing interest, such as18F-FES,cell hypoxia, cell proliferation, and Her-2/neu.

关 键 词：乳腺癌 正电子发射体层成像 体层摄影术 X线计算机 疗效监测 新辅助化疗 新型显像剂 

分 类 号：R737.9[医药卫生—肿瘤]