Estrogen/Huntingtin:a novel pathway involved in neuroprotection  

作　　者：Maria Teresa Nuzzo Maria Marino 

机构地区：[1]Department of Science-Division of Biomedical Sciences and Technologies,University Roma Tre

出　　处：《Neural Regeneration Research》2016年第3期402-403,共2页中国神经再生研究（英文版）

基　　金：supported by Ministero dell’Istruzione,dell’Università e della Ricerca of Italy (PRIN 20109MXHMR_001);Associazione Italiana Ricerca sul Cancro (AIRC,IG#15221)

摘　　要：Neurodegenerative diseases（NDs）include more than 600 disease entities that are characterized by loss of specific neurons located in anatomically related functional areas which progressively lead to motor and cognitive deficits.The pathogenesis of NDs involves mitochondrial dysfunction/oxidative stress,programmed cell death or abnormal protein aggregation,trafficking,and/or degradation.In most cases,Neurodegenerative diseases（NDs）include more than 600 disease entities that are characterized by loss of specific neurons located in anatomically related functional areas which progressively lead to motor and cognitive deficits.The pathogenesis of NDs involves mitochondrial dysfunction/oxidative stress,programmed cell death or abnormal protein aggregation,trafficking,and/or degradation.In most cases,

关 键 词：programmed mitochondrial pathogenesis progressively aggregation oxidative abnormal neuronal caspase physiological 

分 类 号：R741[医药卫生—神经病学与精神病学]