An open-label pilot study with high-dose thiamine in Parkinson's disease  

作　　者：Antonio Costantini Roberto Fancellu 

机构地区：[1]Department of Neurological Rehabilitation,"Villa Immacolata" Clinic [2]Unit of Neurology,IRCCS San Martino University Hospital IST

出　　处：《Neural Regeneration Research》2016年第3期406-407,共2页中国神经再生研究（英文版）

摘　　要：Parkinson’s disease（PD）is a progressive neurodegenerative disorder clinically characterized by motor symptoms（bradykinesia,tremor,rigidity,postural instability）and non-motor symptoms（hyposmia,sleep disorders,autonomic and sphincteric dysfunctions,fatigue,pain,depression,and cognitive disorders）（Sprenger and Poewe,2013）.Parkinson’s disease（PD）is a progressive neurodegenerative disorder clinically characterized by motor symptoms（bradykinesia,tremor,rigidity,postural instability）and non-motor symptoms（hyposmia,sleep disorders,autonomic and sphincteric dysfunctions,fatigue,pain,depression,and cognitive disorders）（Sprenger and Poewe,2013）.

关 键 词：label tremor autonomic instability pilot fatigue rigidity progressive paired dopamine 

分 类 号：R742.5[医药卫生—神经病学与精神病学]