中国近十年急性胰腺炎病因变化特点的Meta分析  

Changes of etiology in acute pancreatitis in recent 10 years in China: Meta-analysis

作　　者：张娜[1] 张海燕[2] 郭晓红[2] 刘立新[2,1] 

机构地区：[1]山西医科大学第一医院消化科 [2]山西医科大学第一医院科研实验中心,太原030001

出　　处：《中华消化病与影像杂志（电子版）》2016年第2期71-75,共5页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：目的评价我国近十年急性胰腺炎(AP)病因变化特点,并比较我国与发达国家病因构成的不同。方法采用Meta分析对入选的23篇有关AP病因的回顾性研究进行汇总、归纳和分析。结果比较2005—2009年和2010—2015年间国内AP常见病因构成的不同,胆源性AP、酒精性AP、高脂血症性AP在2010—2015年时间段发生率升高,且高脂血症性AP已超过酒精性AP,位居第二位;特发性AP的发生率在2010—2015年时间段降低。对比我国与发达国家AP常见病因发生率,发达国家中酒精性AP、特发性AP发生率较高,而我国高脂血症性AP的发生率较高,差异有统计学意义(P<0.05)。结论我国AP存在时间演变,胆源性AP、酒精性AP、高脂血症性AP发生率逐年升高,发达国家与国内情况有所差异,仍以胆源性AP和酒精性AP为主。Objective To evaluate the evolvement of etiology of acute pancreatitis（ AP） in the recent10 years in our country,and to compare the difference of the cause of the disease between China and the developed countries. Methods Meta-analysis was used to evaluate the data extracted from 23 retrospective studies on the etiology of AP. Results In contrast with the different composition of common causes of AP in the recent 10 years,the incidences of biliary AP,alcoholic AP and hyperlipidemia AP significantly increased and hyperlipidemia AP has exceeded alcoholic AP and become the second major cause in the period from2010 to 2015. The incidence of idiopathic AP was lower than that in the period from 2005 to 2010. In contrast with the incidence of common causes of AP between China and developed countries,the incidences of alcoholic AP and idiopathic AP in developed countries were higher than those in China,while the incidence of hyperlipidemia AP in China was higher than that in developed countries. The difference was statistically significant（ P 〈 0. 05）. Conclusion The profile of AP causes changes chronologically in China. The incidences of biliary AP,alcoholic AP and hyperlipidemia AP increase year by year. However biliary AP and alcoholic AP are the main causes in developed countries.

关 键 词：胰腺炎 急性 META分析 病因 

分 类 号：R576[医药卫生—消化系统]