动态血糖监测下胰岛素瘤1例手术前后血糖波动的分析  

Blood Glucose Fluctuation of One Patient with Insulinoma before and after Operation under the Continuous Glucose Monitoring System

作　　者：田坚[1] 杨岚[1] 

机构地区：[1]沈阳医学院附属中心医院内分泌科,辽宁沈阳110024

出　　处：《沈阳医学院学报》2016年第2期89-90,共2页Journal of Shenyang Medical College

摘　　要：目的：研究胰岛素瘤手术前后的动态血糖谱的变化特征,探讨动态血糖监测系统（CGMS）在诊断和指导预后中的应用。方法：选取低血糖原因待查,经病理证实的胰岛素瘤患者1例患者,分析手术前后平均血糖,血糖分布频率及低血糖发生事件的特点。结果：胰岛素瘤手术前后佩带CGMS各3 d,共测血糖1 358个,其中术前血糖平均值6.1 mmol/L,血糖波动范围2.5~10.9 mmol/L,低血糖发生率占15%,发生时间在午夜12时之后及凌晨3时至早晨6时。术后血糖平均值6.8 mmol/L,血糖波动范围5.6~9.0 mmol/L,监测72 h均无低血糖的发生。结论：对于原因不明的低血糖症,行CGMS应用有助于明确病因,胰岛素瘤术前诊断及术后疗效评判,具有临床价值。Objective： To study insulinoma＇s characteristics of blood glucose fluctuation before and after operation. To appraise the value of continuous glucose monitoring system（ CGMS） in the diagnosis of insulinoma and guiding the prognosis. Method： Application of CGMS in dispute over the cause of hypoglycemia,insulinoma was confirmed by pathology and blood glucose monitoring,the mean blood glucose, frequency distribution of glucose levels and the characteristics of the hypoglycemic events was analyzed.Results： The incidence rate of hypoglycemia of the patient with insulinoma before operation accounted for 15%. No hypoglycemia was found in the patient with insulinoma after operation. Conclusion： For unknown cause hypoglycemia,CGMS application helps determine the cause,and CGMS has important value in the preoperative diagnosis of insulinoma and assessment of curative effect.

关 键 词：胰岛素瘤 动态血糖监测系统(CGMS) 低血糖 胰岛素释放指数 

分 类 号：R736.7[医药卫生—肿瘤]