肠脂肪酸结合蛋白对腹部闭合性损伤所致小肠破裂的诊断价值  

Value of intestinal fatty acid binding protein to the diagnosis of small intestinal rupture caused by closed abdominal injuries

作　　者：邢竞晓 欧阳军[1] 

机构地区：[1]石河子大学医学院第一附属医院普外科,新疆石河子832000

出　　处：《中华实用诊断与治疗杂志》2016年第4期361-362,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金(81560312)

摘　　要：目的探讨腹部闭合性损伤所致小肠破裂早期外周血中肠脂肪酸结合蛋白(intestinal fatty acid binding protein,IFABP)的变化。方法随访腹部闭合性损伤患者36例,根据小肠是否破裂分为肠破裂组12例和未破裂组24例,采用ELISA法检测患者入院时、入院1、3h时血清IFABP水平,并进行2组间比较。结果肠破裂组患者血清IFABP水平在入院时[(134.41±53.34)μg/L]、入院1h[(174.68±69.06)μg/L]、入院3h[(186.65±90.08)μg/L]均明显高于未破裂组[(91.44±40.37)、(98.35±44.48)、(104.51±40.08)μg/L](P<0.05)。结论血清IFABP水平检测可用于腹部闭合性损伤所致小肠破裂的早期诊断。Objective To investigate the early change of intestinal fatty acid binding protein（IFABP）in the peripheral blood in small intestinal rupture caused by closed abdominal injuries.Methods Thirty-six patients with closed abdominal injuries were divided into intestinal rapture group（n=12）and non-intestinal rupture group（n=24）.The concentrations of IFABP were detected on admission,and 1 and 3 hours after admission,and were compared between two groups.Results The IFABP concentrations on admission（（134.41±53.34）μg/L）,and 1and 3 hours after admission（（174.68±69.06）,（186.65±90.08）μg/L）in intestinal rupture group were significantly higher than those in non-intestinal rupture group（（91.44±40.37）,（98.35±44.48）,（104.51±40.08）μg/L）（P〈0.05）.Conclusion Serum concentration of IFABP can be used as an indicator for the early diagnosis of small intestinal rupture caused by closed abdominal injuries.

关 键 词：小肠破裂 肠脂肪酸结合蛋白 早期诊断 

分 类 号：R574.5[医药卫生—消化系统]