针刺少阳经特定穴对慢性偏头痛患者脑神经元代谢影响的研究  

Study about Influence of Brain Metabolism in Patients with Chronic Migraine after Acupuncture at Shaoyang Specific Acupoints

作　　者：梁瑞华[1] 张素平[1] 谢永红[1] 

机构地区：[1]暨南大学附属第四医院,广东广州510220

出　　处：《中华中医药学刊》2016年第4期918-920,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：广东省中医药局建设中医药强省科研立项项目(20141219);广州市卫生局医药卫生科技一般引导项目(20151A011016)

摘　　要：目的:探求针刺少阳经特定穴对慢性偏头痛病人脑神经元代谢的影响。方法:慢性偏头痛病人60例,随机分为治疗组治疗组30例,针刺少阳经特定穴;对照组30例,针刺非经非穴。两组病人均在针刺治疗前后进行头痛程度评估、PAG区1H-MRS分析。结果:经针刺治疗后,治疗组较对照组头痛程度减轻,(P<0.05);针刺治疗后,治疗组较对照组PAG区NAA/Cr升高,(P<0.05),两组病人针刺治疗前后PAG区Cho/Cr均无明显差异(P>0.05)。结论:慢性偏头痛病人经针刺少阳经特定穴后PAG区存在神经元代谢活化,可能逆转PAG区异常减弱的疼痛抑制功能。Objective： To explore the influence of brain metabolism in patients with chronic migraine after acupuncture at Shaoyang specific acupoints.Methods： 60 patients with chronic migraine were randomly divided into 2 groups,treatment group（ acupuncture at specific acupoints of Shaoyang） and control group（ acupuncture at non-acupoints）.Both groups were measured1H-MRS metabolic rations at the periaqueductal gray（ PAG） and headache degree evaluation before and after acupuncture.Results： After acupuncture,headache degree of the treatment group was less than the control group＇s（ P〈0.05）.After acupuncture,NAA/Cr ration at the PAG of the treatment group was higher than the control group＇s（ P〈0.05）.The Cho/Cr ratios at the PAG of the two groups had no difference（ P〈0.05）.Conclusion： Neuronal metabolic activation exits at the PAG in patients with chronic migraine after acupuncture at Shaoyang specific acupoints.Acupuncture at Shaoyang specific acupoints may reverse the abnormally decreased pain inhibitory function at PAG.

关 键 词：慢性偏头痛 针刺 少阳经 中脑导水管周围灰质 磁共振氢质子波谱 

分 类 号：R747.2[医药卫生—神经病学与精神病学]