云南球花石斛花化学成分的研究（英文）  

Chemical Constituents from the Flowers of Dendrobium thyrsiflorum

作　　者：陈亚萍[1] 李玉鹏[1] 张中[1] 张君[1] 张凯丽[1] 黄荣[2] 文小玲[1,3] 

机构地区：[1]昆明医科大学药学院暨云南省天然药物药理重点实验室,云南昆明650500 [2]云南大学现代分析测试中心,云南昆明650091 [3]昆明医科大学人事处,云南昆明650500

出　　处：《昆明医科大学学报》2016年第1期5-7,共3页Journal of Kunming Medical University

基　　金：supported by grants from the National Natural Science Foundation of China(21202066);the Natural Science Foundation of Yunnan Province,China(2012FB156);the project for Excelient Young Teccher of Kunming Medical University and Yunan Province(J1301306611,6011521120);the Foundation from Educational Department of Yunnan Province(2015Y151);the Open Research Foundation of Yunnan Key Laboratory of Pharmacology for Natural Products(2014G011)

摘　　要：目的研究云南球花石斛花化学成分,发现其活性成分.方法球花石斛花溶剂提取、硅胶柱层析和Sephadex LH-20柱层析进行分离纯化,波谱分析(核磁共振氢谱、碳谱、和质谱)确定结构.结果从该药用植物花乙酸乙酯萃取部分分离并鉴定了7个化合物,分别为:β-sitosterol(1),stigmasterol(2),6,7-dimethoxy coumarin(3),6-methoxy-7-hydroxy coumarin(4),dibutyl phthalate(5),naringenin(6),daucosterol(7).结论所有化合物均为首次从本植物花中分离得到.Objective To study the chemical constituents from the flowers of Dendrobium thyrsiflorum and find its bioactive compounds. Methods The compounds were extracted by 95% alcohol and isolated by column chromatography on silica gel and Sephadex LH-20. Their structures were identified by spectroscopic analysis（1H NMR,13 CNMR and EIMS）.Results Seven compouds were obtained and identified as β-sitosterol（1）,stigmasterol（2）,6,7-dimethoxy coumarin（3）,6-methoxy-7-hydroxy coumarin（4）,dibutyl phthalate（5）,naringenin（6）,daucosterol（7）.Conclusion All compounds were isolated from the flowers for the first time.

关 键 词：球花石斛 药用植物 化学成分 

分 类 号：R284.2[医药卫生—中药学]