肝动脉插管栓塞化疗后原发性肝癌血清AFP变化与疗效的关系  

Relationship between Serum AFP Level Changes and Efficacy of Transcatheter Arterial Chemoembolization(TACE)in Primary Liver Cancer

作　　者：李美琴[1] 朱春燕[1] 黄蕾[1] 刘金凤[1] 谢娟[1] 黄玲莎[1] 

机构地区：[1]广西医科大学附属肿瘤医院检验科,广西南宁530021

出　　处：《蛇志》2016年第1期15-16,共2页Journal of Snake

摘　　要：目的探讨肝动脉插管栓塞化疗(TACE)后原发性肝癌患者血清AFP变化与疗效的关系。方法对TACE治疗的64例原发性肝癌患者,于介入前、介入后1月,行上腹部CT检查以及测定患者血清AFP水平,观察其疗效和AFP值变化。结果有效组(包括PR组和SD组)44例介入前后AFP值比较差异具有显著性(P<0.05),PD组20例介入前后AFP值比较差异有显著性(P<0.05)。PR组(22例)和SD组(22例)介入前后AFP差值比较,差异无显著性(P>0.50)。结论原发性肝癌患者血清AFP水平的变化对评价TACE疗效具有重要的临床价值。Objective To explore the relationship between serum AFP level changes and efficacy of transcatheter arterial chemoembolization（TACE）in primary liver cancer. Methods The use of transcatheter arterial chemoembolization（TACE）treatment of 64 cases of patients with primary liver cancer,TACE before and after 1months,test upper abdomen CT and measure serum AFP levels,observe the efficacy and AFP changes. Results There was significant difference in the AFP changes of effective group（n=44,including PR group and SD group）after TACE（P〈0.05）,there was significant difference in the AFP changes of PD group（n=22）after TACE.There were no significant difference between the PR group and SD group in the AFP changes（P〉0.05）. ConclusionDetecting of serum AFP changes is of important clinical significance for the evaluation of the rapeutic efficacy of TACE in patients with primary liver cancer.

关 键 词：原发性肝癌 肝动脉介入栓塞术 甲胎蛋白 

分 类 号：R735.7[医药卫生—肿瘤]