Establish Albumin-creatinine Ratio Reference Value of Adults in the Rural Area of Hebei Province  

作　　者：Qiao-jing Liang Wen Huang Guo-juan Zhang Ning-li Wang 

机构地区：[1]Department of Nephrology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University [2]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University

出　　处：《Chinese Medical Sciences Journal》2016年第1期23-30,共8页中国医学科学杂志（英文版）

基　　金：Supported by the National Basic Research Program of China(973 Program)(2007CB512201);the Program of Health Policy for blindness prevention from China;the Key Technologies R&D Program(2006-10903)from the Science and Technology Bureau of Handan City,Hebei Province,China;a program from Beijing Tongren Hospital;key discipline fund of Health Bureau,Handan City,Hebei Province,China

摘　　要：Objective To establish albumin-creatinine ratio （ACR） reference value of the rural population in Hebei province. Methods This study enrolled 5154 participants. By excluding subjects with hypertension, diabetes, dyslipidemia, cardiovascular and cerebrovascular diseases, kidney diseases, and overweight condition, as well as those with an estimated glomerular filtration rate （eGFR）（60 ml/（min· 1.73 m^2）, apparently healthy subjects （1168） were selected. Urine albumin was measured by using the immunoturbidimetic method, serum creatinine was measured by using Jaffe＇s kinetic method on a morning spot-urine sample, and ACR was calculated. The 95th percentile of ACR in the healthy subjects was used as the normal upper limit. Results The normal upper limit of ACR was 28.71 mg/g （3.25 mg/retool） for males and 31.85 mg/g （3.60 rag/retool） for females. Based on this ACR reference value, the age-gender standardized prevalence of albuminuria in the rural areas of Hebei province was 12.9%. Conclusion The ACR reference value in the rural of Hebei province is higher than that of the Western population.

关 键 词：albumin-creatinine ratio ALBUMINURIA chronic kidney disease 

分 类 号：R446.1[医药卫生—诊断学]