Supported by the National Research Foundation(NRF)of Korea,No.RS-2023-00217317。
BACKGROUND Diabetes is a significant risk factor for chronic kidney disease,and diabetic kidney disease(DKD)is prevalent among patients with diabetes.Previous studies have indicated that the duration of diabetes and p...
The underlying molecular changes that result in minimal change disease(ne-phrotic syndrome)require an in-depth analysis.Current molecular studies have shown the involvement of zinc fingers and homeobox transcriptional...
the Key R&D Project of the Ministry of Science and Technology,No.2016YFC0901200 and 2016YFC0901205.
BACKGROUND Diabetic kidney disease is one of the common complications of type 2 diabetes(T2D).There are no typical symptoms in the early stage,and the disease will progress to moderate and late stage when albuminuria ...
Objective To investigate the prevalence of albuminuria in Chinese residents aged>35 years and its potential association with cardiovascular disease(CVD).Methods A total of 34647 Chinese subjects aged≥35 years were se...
Objective To explore the relationship between metabolic score for insulin resistance(METS-IR)and chronic kidney disease(CKD)and albuminuria in the Chinese population.Methods This cross-sectional study was conducted fr...
BACKGROUND Diabetes mellitus is considered a leading contributor to severe coronavirus disease 2019(COVID-19).AIM To characterize differences between hospitalized diabetic patients with vs without COVID-19,and paramet...
This work was supported by the grants from the National Key R&D Program of China(Nos.2017YFC1310700,2018YFC1311800,and 2018YFC1311705);the National Natural Science Foundation of China(Nos.81870560,82070880,81941017,81770842,81970706,and 82022011);the National Science and Technology Major Project for"Significant New Drugs Development"(No.2017ZX09304007);Shanghai Municipal Government(No.18411951800);Shanghai Shenkang Hospital Development Center(Nos.SHDC12019101,SHDC2020CR1001A,and SHDC2020CR3069B);the Scientific and Technological Committee of Shanghai(No.19411964200);Shanghai Jiao Tong University School of Medicine(No.DLY201801);Ruijin Hospital(No.2018 CR002);Shanghai Rising-Star Program(No.21QA1408100).
A new definition of metabolic dysfunction-associated fatty liver disease(MAFLD)has recently been proposed.We aim to examine the associations of MAFLD,particularly its discordance from non-alcoholic fatty liver disease...
This work was supported by the grant from the National Natural Science Foundation of China(No.81870570).
The presence of senescent cells is associated with renal fibrosis.This study aims to investigate the effect of albumininduced premature senescence on tubulointerstitial fibrosis and its possible mechanism in vitro.Dif...
Introduction: Inflammation has been implicated as a major reason for the higher morbidity and mortality in chronic kidney disease (CKD) compared to the diseases that commonly precedes it. The neutrophil lymphocyte rat...