重症急性胰腺炎患者早期腹腔灌洗的临床疗效  

Clinical effect of early peritoneal lavage in patients with severe acute pancreatitis

作　　者：李燕[1] 朱晓琼[1] 张先玲[1] 尹微[1] 贾民[1] 

机构地区：[1]新疆医科大学第五附属医院ICU,乌鲁木齐830000

出　　处：《临床急诊杂志》2016年第3期227-229,共3页Journal of Clinical Emergency

摘　　要：目的:探讨早期腹腔灌洗治疗重症急性胰腺炎的临床疗效。方法:以我院重症监护室收治的68例重症急性胰腺炎患者作为研究对象,根据随机数字表法分为对照组与观察组,每组34例。对照组给予临床常规治疗,观察组在对照组的基础上给予早期腹腔灌洗治疗,对比分析2组患者的治疗效果及治疗前后APACHEⅡ、腹水淀粉酶的变化情况等。结果:观察组治疗总有效率为88.2%,显著高于对照组的73.5%,多器官功能障碍综合征(MODS)发生率为5.9%,显著低于对照组的26.5%(P<0.05);治疗前2组患者APACHEⅡ、腹水淀粉酶比较,差异无统计学意义;治疗后,观察组APACHEⅡ评分和腹水淀粉酶水平显著低于对照组,住院时间显著短于对照组(P<0.05)。结论:在常规治疗的基础上给予早期腹腔灌洗治疗,可有效提升重症急性胰腺炎的治疗效果,缩短治疗时间,减少并发症的发生,促进患者尽快恢复健康,具有较高应用价值。Objective：To explore the clinical effect of early peritoneal laoage in patients with severe acute pancreatitis.Method：Sixty-eight cases of severe acute pancreatitis in intensive care unit of our hospital were admitted as the research objects.They were divided into control group and observation group according to random number table method,34 cases in each group.Patients of control group were given routine clinical treatment.Patients of the observation group were given early abdominal cavity lavage treatment on the basis of routine clinical treatment.The therapeutic effect of two groups,APACHE Ⅱ before and after the treatment,changes of ascites amylase and so on were compared.Result：The total effective rate of the observation group was 88.2%.It was obviously higher than that of control group（73.5%）.MODS incidence of the observation group was 5.9%,lower than that of the control group（26.5%）（P〈0.05）.APACHE Ⅱ,ascites amylase of the two groups before treatment have no significant difference.After treatment,APACHE Ⅱscore and ascites amylase levels of the observation group were lower than that of the control group.Length of hospital stay and systemic inflammatory response duration of the observation group were shorter than that of the control group（P〈0.05）.Conclusion：On the basis of conventional treatment,early abdominal cavity lavage treatment can effectively improve the therapeutic effect of severe acute pancreatitis,shorten the treatment time,reduce complications,promote patients recover as soon as possible.It has high application value.

关 键 词：重症急性胰腺炎 早期腹腔灌洗治疗 临床疗效 

分 类 号：R576[医药卫生—消化系统]