64排螺旋CT低剂量在高危人群早期肺癌筛查和诊断中的应用价值  

Application of 64 slice spiral CT low dose in early screening and diagnosis of lung cancer in high riskpopulation

作　　者：史利红[1] 

机构地区：[1]唐山市人民医院CT室,063000

出　　处：《国际呼吸杂志》2016年第4期258-261,共4页International Journal of Respiration

摘　　要：目的探讨64排螺旋CT低剂量在高危人群早期肺癌筛查和诊断中的应用价值。方法以本院2013年1月至2015年12月期间我院体检中心体检的1036例高危人群作为研究对象，分别采用X光机和CT机进行早期肺部癌症筛查。获得DR胸片和CT影像后由2位医师采用双盲法对影像进行观察并作出诊断。记录肺部结节数量、大小和最终诊断结果。结果采用CT扫描出肺部结节病灶共169例，检出率为16．31％；而采用DR胸片共检出76例，检出率为7．34％。2种方法在肺部结节检出率之间的差异有统计学意义（X2=40．036o，P〈0．05），CT扫描检出率优于DR胸片检出率。2种方法在检出肺部不同大小结节数之间的差异有统计学意义（X2=9．6688，P〈0．05）。2种方法在〉10mm结节检出率之间的差异有统计学意义（X2=4．6677，P〈0．05）。在1036例样本中，CT扫描确诊肺癌20例（1．93％），DR胸片确诊肺癌6例（0．58％）。2种方法在肺癌筛查确诊率之间的差异有统计学意义（X2=6．5826，P＜0．05），CT扫描检出肺癌率要优于DR胸片检查。结论针对肺癌高危人群的早期筛查工作，64排螺旋CT低剂量扫描对筛查肺部结节和确诊疾病并及时制定临床救治方案具有指导意义，适于推广与应用。Objective To study the application value of 64 slice spiral CT low dose in early screening and diagnosis of lung cancer in high risk population. Methods 1 036 cases of high risk in medical examination center of our hospital from January 2013 to December 2015 were recruited as the research object. X-ray and CT were used for early screening of lung cancer respectively. DR chest radiography and CT images were checked by two doctors using double blind method to make diagnosis. The number and size of the pulmonary nodules and the final diagnosis results were recorded. Results 169 cases of pulmonary nodules were scanned with CT, the detection rate was 16.31%, while 76 cases were scanned with DR, the detection rate was 7.34%. The difference between the two methods was statistically significant （ X^2=40. 036 0, P〈0.05）, and the detection rate of CT was superior to DR. The difference between the two methods in the detection of different size of the lung nodules was statistically significant （X2= 9. 668 8, P 〈0.05）. The difference between the two methods in the detection rate of more than 10 mm nodules was statistically significant （ X2 = 4. 667 7, P 〈0.05）. In 1 036 cases, CT scan showed that 20 cases （1.93%） were detected as lung cancer, while six cases （0.58%） were diagnosed as lung cancer by DR method. The difference between the two methods in the diagnosis of lung cancer was statistically significant （ X2= 6. 582 6, P 〈0.05）, and the detection rate of lung cancer by CT scan was higher than that by DR. Conclusions 64 slice spiral CT low dose scanning has guiding significance in the screening of pulmonary nodules, the diagnosis of lung cancer and timely development of clinical treatment plan for the screening of lung cancer risk population, and is suitable for popularization and application.

关 键 词：64排螺旋CT 低剂量扫描 肺癌 筛查 诊断 

分 类 号：R734.2[医药卫生—肿瘤]