合并桥本病的甲状腺乳头状癌的临床研究及外科治疗  

Clinical research and surgical treatment of Hashimoto's disease complicated with papillary thyroid carcinoma

作　　者：陈征[1] 董汉华[1] 叶真[2] 

机构地区：[1]郑州大学附属郑州中心医院甲状腺头颈外科,郑州450007 [2]河南省肿瘤医院头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2016年第7期532-534,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:通过对桥本病合并甲状腺乳头状癌的相关临床参数的研究分析,探讨桥本病对甲状腺乳头状癌侵袭性的影响及外科治疗。方法:回顾性分析312例甲状腺乳头状癌患者,其中包括70例桥本病合并甲状腺乳头状癌患者(观察组),242例单纯性甲状腺乳头状癌患者(对照组)。结果:观察组与对照组在性别、肿瘤大小、甲状腺抗体水平及中央区淋巴结转移方面差异有统计学意义(P<0.05)。结论:桥本病是甲状腺乳头状癌的一种保护性因素,合并桥本病的甲状腺乳头状癌病灶直径更小,有更低的淋巴结转移,对合并桥本病的甲状腺乳头状癌患者宜在采取手术原发灶根治的同时行中央区淋巴结清扫,尽量避免预防性颈侧淋巴结清扫。Objective：To analyze the clinical characteristics of Hashimoto＇s disease complicated with papillary thyroid carcinoma and research surgical treatment and Hashimoto＇s disease＇s effect to papillary thyroid carcinoma.Method：Three hundred and twelve cases of papillary thyroid carcinoma were retrospectively reviewed.Among 70 cases of papillary thyroid carcinoma associated Hashimoto＇s disease（the observation group）,242 cases of single papillary thyroid carcinoma（the control group）.Result：The observation group compared with the control group,there was a significant difference in gender,tumor size,thyroid antibody level and the lymph node metastasis,with statistical significance（P〈0.05）.Conclusion：Hashimoto＇s disease is a kind of protective factors of thyroid papillary carcinoma,Hashimoto＇s disease with coexistent papillary thyroid carcinoma is smaller in tumor diameter and have lower lymph node metastasis.Surgery takes the original operation primary radical and central lymph node dissection,try to avoid the preventive side neck lymph node dissection.

关 键 词：桥本病 甲状腺肿瘤 外科治疗 

分 类 号：R736.1[医药卫生—肿瘤]