MINE方案治疗32例复发或难治性中高危非霍奇金淋巴瘤的疗效观察  

The clinical efficacy of 32 patients with recurrent and refractory non-hodgkin's lymphoma treated with MINE regimen

作　　者：李路路[1] 陈剑[1] 张鼎儒[1] 

机构地区：[1]河南省焦作市第二人民医院放疗科,河南焦作454001

出　　处：《中国现代医生》2016年第8期66-68,共3页China Modern Doctor

摘　　要：目的观察MINE方案作为复发或难治性中高危非霍奇金淋巴瘤（NHL）的疗效和安全性。方法选取我院2012年1月～2015年10月收治的32例复发或难治性中高危NHL患者,使用MINE方案作为解救方案进行化疗;观察患者的近期疗效和毒副反应。结果 32例患者分别接受了2～6个周期的MINE方案化疗,总有效率为53.1%,完全缓解率为18.8%;主要毒副反应为骨髓抑制,可以耐受。结论 MINE方案为复发或难治性中高危NHL的安全有效的解救方案之一。Objective To observe the efficacy and safety of MINE regimen treated patients with medium and high risk NHL. Methods From January 2012 to October 2015, 32 patients who were failing to responded to first line chemotherapy like NHL regimen received MINE regimen for salvage. The response rate, complete resonse, and adverse effect were evaluated. Results The total response rate of 32 patients who accepted 2-6 cycles MINE regimen respectively was53.1%, complete response was 18.8%, and the myelosuppression was the chief adverse effect. Conclusion The MINE regimen is a efficacy and safety choice for medium and high risk NHL patients.

关 键 词：非霍奇金淋巴瘤 解救治疗 MINE方案 

分 类 号：R733.4[医药卫生—肿瘤]