C-反应蛋白与血清白细胞介素-18检验对急性脑梗死的意义研究  

Study on the Significance of C-reactive Protein and Serum Interleukin-18 Test in Acute Cerebral Infarction

作　　者：纪小霞[1] 陈愉 吴阿阳[3] 刘淑亮[4] 

机构地区：[1]福建医科大学附属漳州市医院检验科,福建漳州363000 [2]莆田95医院检验病理科,福建莆田351100 [3]福建医科大学附属漳州市医院检验病理科,福建漳州363000 [4]福建医科大学附属漳州市医院放射科,福建漳州363000

出　　处：《中外医疗》2016年第7期10-12,共3页China & Foreign Medical Treatment

摘　　要：目的 探索研究急性脑梗死患者C-反应蛋白与血清白细胞介素-18(IL-18)两项指标的临床研究意义。方法整群选取2014年6月—2015年6月住院治疗的急性脑梗死患者103例(试验组)和门诊体检结果健康者98例(对照组),检测其C-反应蛋白和白细胞介素-18指标,结果进行统计分析。结果同对照组健康者对比,试验组急性脑梗死患者的血清白细胞介素-18和C-反应蛋白的检验指标显著增高(P<0.05),试验组患者不同时间检验结果相互比较,发病第3日两项指标结果均显著高于其他时间值(P<0.05);试验组中脑梗死程度高的患者,其指标值显著高于程度较轻患者的指标值(P<0.05)。结论通过检测C-反应蛋白和血清白细胞介素-18指标,可对急性脑梗死患者疾病严重程度进行评价和其预后进行参考。Objective To explore the clinical significance of C-reactive protein and serum interleukin-18 these two indicators in acute cerebral infarction. Methods The measurement of C-reactive protein and serum interleukin-18 levels was performed in 103 cases with acute cerebral infarction（test group） underwent inpatient treatment from June 2014 to June 2015 and 98 healthy controls underwent physical examination in the outpatient during the same period and had normal results（control group）. The results of the measurement were analyzed statistically. Results The C-reactive protein and serum interleukin-18 levels were much higher in the test group than those in the control group（P〈0.05）. The C-reactive protein and serum interleukin-18 levels in the test group on the third day after the onset were the highest compared with those at other times（P0.05）. In the test group, the C-reactive protein and serum interleukin-18 levels were much higher in the patients with more severe acute cerebral infarction than in those with milder acute cerebral infarction（P0.05）. Conclusion The measurement results of C-reactive protein and serum interleukin-18 levels can provide a reference for the evaluation of the severity and prognosis of acute cerebral infarction.

关 键 词：C-反应蛋白 血清白细胞介素-18 急性脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学]