抽动障碍患儿及父母心理干预的临床研究  

Clinical study on psychological interventions for pediatric patients with Tic disorder and their parents

作　　者：房夏玲[1] 高文娟[1] 陈宁[1] 刘小红[1] 史瑞明[1] 

机构地区：[1]西安交通大学第一附属医院儿科,陕西西安710061

出　　处：《中国妇幼健康研究》2016年第3期329-331,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨抽动障碍患儿及父母的心理干预在辅助药物治疗儿童抽动障碍中的重要作用。方法收集西安交通大学第一附属医院儿科门诊就诊的50例抽动障碍患儿,随机分为研究组和对照组各25例,研究组采用氟哌啶醇(0.025mg/kg起始剂量,根据症状缓解情况调整至最佳治疗量,最大治疗量2mg/d)联合患儿及父母心理干预的治疗措施,对照组采用单用氟哌啶醇药物治疗(剂量同前),治疗8周后观察其疗效及安全性。结果 50例抽动障碍患儿中,男37例,女13例,64%(32/50)为学龄期儿童,主要表现为频繁眨眼或(和)耸肩,72%(36/50)出现两个以上部位的抽动。研究组治疗的总有效率达88%,显著高于单纯药物治疗组60%,二者具有统计学差异(x^2=5.049,P<0.05)。两组患儿均无严重不良药物反应。结论小剂量氟哌啶醇治疗儿童抽动障碍起效快、疗效好、有较好的安全性,同时患儿及父母的心理干预治疗尤为重要,加强心理知识培训,药物治疗的给与患儿及家属早期的心理咨询和干预处理,减轻家庭的沉重负担,获得经济和社会效益。Objective To explore the important role of psychological interventions for patients and their parents in assisting drug therapy to treat children with Tic disorder （TD）. Methods A total of 50 cases of pediatric TD patients were collected and divided into two groups, study group and control group. All those patients received treatments at the pediatrics department of the First Affiliated Hospital of Xi＇ an Jiaotong University. As for patients in the study group, they received haloperidol （started with an initial dose of 0. 025mg/kg; adjusted the dosage to the best therapeutic dose in accordance with the relief of clinical symptoms; the maximum dose was 2mg/d） combined with psychological interventions for patients and their parents. Patients in the control group received haloperidol （ the same as the study group in dose）. Therapeutic effects and safety of the preceding treatments were observed 8 weeks after their receiving those treatments. Results Among 50 cases of TD patients, 37 cases were male patients while 13 cases were female. Totally 64% （32/50） of the patients were children of school age. The main clinical manifestations were frequent winking or （and） shrugging. There were 72% （36/50） presenting twitching in two or more parts of body. The total effective rate reached 88% in the study group, which was significantly higher than that in the control group （60%）. The preceding difference was of statistical significance （χ^2= 5. 049, P 〈 0.05 ）. No children at both groups experienced severe adverse drug reactions. Conclusion Low dose of haloperidol takes effect quickly, has a good efficacy and relatively good safety in treating children with TI）. Besides, psychological interventions for both patients and their parents are of great importance. Psychological knowledge training should be strengthened. In addition, it is necessary to carry out early psychological counseling and psychological interventions for patients and their family members when patients are receiving drug th

关 键 词：儿科 抽动障碍 心理干预 临床研究 

分 类 号：R749.94[医药卫生—神经病学与精神病学]